iPTMnet Report for O43741 (PRKAB2)
Protein Information
| UniProt AC / UniProt ID | O43741 / AAKB2_HUMAN |
| Protein Name | 5'-AMP-activated protein kinase subunit beta-2 |
| Gene Name | Name: PRKAB2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O43741 |
| PRO Name | 5'-AMP-activated protein kinase subunit beta-2 (human) |
| Definition | A 5'-AMP-activated protein kinase subunit beta-2 that is encoded in the genome of human. |
| Short Label | hPRKAB2 |
| Category | organism-gene |
DAG ViewO43741 (PRKAB2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S39 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S95 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S108 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19369195, 21406692, 23186163, ... | ||
| T148 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 26831516, 24275569 | ||
| K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S170 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| Y189 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| Y194 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y263 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K270 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18669648, ... | ||
| T40 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
| S108 | Phosphorylation | score0 | HPRD | 20166139, 18691976, 18669648, ... | ||
| T148 | Phosphorylation | score0 | HPRD | 20166139 | ||
| S158 | Phosphorylation | score0 | HPRD | 20166139 | ||
| S173 | Phosphorylation | score0 | HPRD | 20166139 | ||
| S182 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S183 | Phosphorylation | score0 | HPRD | 19415658 | ||
| S184 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 19651622, ... | ||
| Y189 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S21 | A21 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K57 | N57 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S69 | F69 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S93 | Y93 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S158 | F158 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] | |
| S182 | P182 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S182 | F182 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
| K270 | M270 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
