iPTMnet Report for O43593 (HR)
Protein Information
UniProt AC / UniProt ID | O43593 / HAIR_HUMAN |
Protein Name | Lysine-specific demethylase hairless |
Gene Name | Name: HR |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43593 |
PRO Name | lysine-specific demethylase hairless (human) |
Definition | A lysine-specific demethylase hairless that is encoded in the genome of human. |
Short Label | hHR |
Category | organism-gene |
O43593 (HR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
S316 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
R574 | Methylation | score1 | PhosphoSitePlus | |||
S601 | Phosphorylation | score1 | PhosphoSitePlus | |||
T610 | Phosphorylation | score1 | PhosphoSitePlus | |||
T631 | Phosphorylation | score1 | PhosphoSitePlus | |||
K708 | Ubiquitination | score1 | PhosphoSitePlus | |||
K733 | Sumoylation | score1 | PhosphoSitePlus | |||
K812 | Ubiquitination | score1 | PhosphoSitePlus | |||
S833 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S316 | F316 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S316 | C316 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
R574 | W574 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |