iPTMnet Report for O43548 (TGM5)
Protein Information
UniProt AC / UniProt ID | O43548 / TGM5_HUMAN |
Protein Name | Protein-glutamine gamma-glutamyltransferase 5 |
Gene Name | Name: TGM5 Synonyms:TGMX; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43548 |
PRO Name | protein-glutamine gamma-glutamyltransferase 5 (human) |
Definition | A protein-glutamine gamma-glutamyltransferase 5 that is encoded in the genome of human. |
Short Label | hTGM5 |
Category | organism-gene |
O43548 (TGM5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score2 | UniProt | 15290349 | ||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
T484 | Phosphorylation | score1 | PhosphoSitePlus | |||
S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
S493 | O-Glycosylation | score1 | GlyGen | 30379171, 35254053 | ||
S498 | O-Glycosylation | score1 | GlyGen | 30379171, 35254053 | ||
Y575 | Phosphorylation | score1 | PhosphoSitePlus | |||
C577 | Methylation | score1 | IEDB | 31844290 | ||
Y581 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y587 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | T2 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
T484 | K484 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
C577 | Y577 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y581 | D581 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |