iPTMnet Report for O43548 (TGM5)
Protein Information
| UniProt AC / UniProt ID | O43548 / TGM5_HUMAN |
| Protein Name | Protein-glutamine gamma-glutamyltransferase 5 |
| Gene Name | Name: TGM5 Synonyms:TGMX; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O43548 |
| PRO Name | protein-glutamine gamma-glutamyltransferase 5 (human) |
| Definition | A protein-glutamine gamma-glutamyltransferase 5 that is encoded in the genome of human. |
| Short Label | hTGM5 |
| Category | organism-gene |
O43548 (TGM5) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score2 | UniProt | 15290349 | ||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T484 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S493 | O-Glycosylation | score1 | GlyGen | 30379171, 35254053 | ||
| S498 | O-Glycosylation | score1 | GlyGen | 30379171, 35254053 | ||
| Y575 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C577 | Methylation | score1 | IEDB | 31844290 | ||
| Y581 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y587 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | T2 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T484 | K484 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| C577 | Y577 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y581 | D581 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
DAG View