iPTMnet Report for O43396 (TXNL1)
Protein Information
UniProt AC / UniProt ID | O43396 / TXNL1_HUMAN |
Protein Name | Thioredoxin-like protein 1 |
Gene Name | Name: TXNL1 Synonyms:TRP32,TXL,TXNL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43396 |
PRO Name | thioredoxin-like protein 1 (human) |
Definition | A thioredoxin-like protein 1 that is encoded in the genome of human. |
Short Label | hTXNL1 |
Category | organism-gene |
O43396 (TXNL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score0 | HPRD | 20068231 | ||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
C34 | S-Nitrosylation | score2 | dbSNO | 23796488, 23010496 | ||
C37 | S-Nitrosylation | score2 | dbSNO | 23796488, 23010496 | ||
S46 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S48 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
S113 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20166139, 23186163 | ||
T117 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
C149 | Methylation | score1 | IEDB | 31844290 | ||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y262 | Phosphorylation | score1 | PhosphoSitePlus | |||
T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
K279 | Acetylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S46 | F46 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S48 | I48 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T117 | K117 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S141 | I141 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K181 | T181 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K195 | N195 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
K226 | T226 | Biomuta | [ cosmic ] |