iPTMnet Report for O15169 (AXIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15169 / AXIN1_HUMAN
Protein Name Axin-1
Gene Name Name: AXIN1
Synonyms:AXIN;
Organism Homo sapiens (Human)

PRO ID PR:O15169
DAG View
PRO Name Axin-1 (human)
Definition An Axin-1 that is encoded in the genome of human.
Short Label hAXIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15169 (AXIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S46 Phosphorylation Signor 12000790
S46 Phosphorylation P48730 (CSNK1D) Signor 12000790
T60 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus   UniProt 17318175
S77 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17318175
T79 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
S157 Phosphorylation RLIMS-P+ 23155463
S157 Phosphorylation P53350 (PLK1) RLIMS-P+ 23155463
T160 Phosphorylation PhosphoSitePlus
T213 Phosphorylation phospho.ELM 18669648
S217 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17318175
K387 Ubiquitination PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus   UniProt 17318175
T481 Phosphorylation neXtProt   PRO   PhosphoSitePlus   Signor 21940452, 10581160
T481 Phosphorylation P49841 (GSK3B) neXtProt   Signor 10581160
T481 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 21940452
S486 Phosphorylation neXtProt   PRO   PhosphoSitePlus   Signor   UniProt 10581160, 23186163
S486 Phosphorylation P49841 (GSK3B) neXtProt   Signor 10581160
S493 Phosphorylation PRO   PhosphoSitePlus
K501 Ubiquitination PRO
S511 Phosphorylation PhosphoSitePlus   UniProt 23186163
R576 Methylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus   UniProt 23186163
S611 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation PhosphoSitePlus
Y788 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation HPRD 18669648
Y148 Phosphorylation HPRD 18491316
T160 Phosphorylation HPRD 18491316
T213 Phosphorylation HPRD 18669648
S217 Phosphorylation HPRD 18669648
S493 Phosphorylation HPRD 19651622
S614 Phosphorylation HPRD 10581160
S614 Phosphorylation P49841 (GSK3B) HPRD 10581160
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation HPRD 18669648
Y148 Phosphorylation HPRD 18491316
T160 Phosphorylation HPRD 18491316
T213 Phosphorylation HPRD 18669648
S217 Phosphorylation HPRD 18669648
S493 Phosphorylation HPRD 19651622
S614 Phosphorylation HPRD 10581160
S614 Phosphorylation P49841 (GSK3B) HPRD 10581160
K789 Ubiquitination PhosphoSitePlus
K821 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046443 (hAXIN1/ADPribUbiq+) ub PRO
PR:000046444 (hAXIN1/Phos:1) pT481,pS486,pS493 PRO
PR:000046445 (hAXIN1/Ubiq:1) ubK501 PRO


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036448 (hMYC/iso:1/Phos:1) Interaction PR:O15169-1 (hAXIN1/iso:1) PRO 19131971
PR:O15169-1 (hAXIN1/iso:1) Interaction PR:000036448 (hMYC/iso:1/Phos:1) PRO 19131971