iPTMnet Report for O15169 (AXIN1)
Protein Information
UniProt AC / UniProt ID | O15169 / AXIN1_HUMAN |
Protein Name | Axin-1 |
Gene Name | Name: AXIN1 Synonyms:AXIN; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15169 |
PRO Name | Axin-1 (human) |
Definition | An Axin-1 that is encoded in the genome of human. |
Short Label | hAXIN1 |
Category | organism-gene |
O15169 (AXIN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Ubiquitination | score1 | PRO | ||||
S46 | Phosphorylation | P48730 (CSNK1D) | score1 | Signor | 12000790 | |
T60 | Phosphorylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 17318175 | ||
S77 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 17318175 | ||
T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S157 | Phosphorylation | P53350 (PLK1) | score2 | RLIMS-P+ | 23155463 | |
T160 | Phosphorylation | score1 | PhosphoSitePlus | |||
T213 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S217 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17318175 | ||
K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
S469 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 17318175 | ||
T481 | Phosphorylation | P49841 (GSK3B) , Q00535 (CDK5) | score4 | neXtProt PRO PhosphoSitePlus Signor | 21940452, 10581160 | |
S486 | Phosphorylation | P49841 (GSK3B) | score4 | neXtProt PRO PhosphoSitePlus Signor UniProt | 10581160, 23186163 | |
S493 | Phosphorylation | score2 | PRO PhosphoSitePlus | |||
K501 | Ubiquitination | score1 | PRO | |||
S511 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R576 | Methylation | score1 | PhosphoSitePlus | |||
S581 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S611 | Phosphorylation | score1 | PhosphoSitePlus | |||
S614 | Phosphorylation | score1 | PhosphoSitePlus | |||
S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
T617 | Phosphorylation | score1 | PhosphoSitePlus | |||
S623 | Phosphorylation | score1 | PhosphoSitePlus | |||
S644 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y787 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y788 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y796 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S77 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y148 | Phosphorylation | score0 | HPRD | 18491316 | ||
T160 | Phosphorylation | score0 | HPRD | 18491316 | ||
T213 | Phosphorylation | score0 | HPRD | 18669648 | ||
S217 | Phosphorylation | score0 | HPRD | 18669648 | ||
S493 | Phosphorylation | score0 | HPRD | 19651622 | ||
S614 | Phosphorylation | P49841 (GSK3B) | score1 | HPRD | 10581160 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S77 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y148 | Phosphorylation | score0 | HPRD | 18491316 | ||
T160 | Phosphorylation | score0 | HPRD | 18491316 | ||
T213 | Phosphorylation | score0 | HPRD | 18669648 | ||
S217 | Phosphorylation | score0 | HPRD | 18669648 | ||
S493 | Phosphorylation | score0 | HPRD | 19651622 | ||
S614 | Phosphorylation | P49841 (GSK3B) | score1 | HPRD | 10581160 | |
K789 | Ubiquitination | score1 | PhosphoSitePlus | |||
K821 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000046443 (hAXIN1/ADPribUbiq+) | ub | PRO | |||
PR:000046444 (hAXIN1/Phos:1) | pT481,pS486,pS493 | PRO | |||
PR:000046445 (hAXIN1/Ubiq:1) | ubK501 | PRO |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:000036448 (hMYC/iso:1/Phos:1) | Interaction | PR:O15169-1 (hAXIN1/iso:1) | PRO | 19131971 | |
PR:O15169-1 (hAXIN1/iso:1) | Interaction | PR:000036448 (hMYC/iso:1/Phos:1) | PRO | 19131971 |