iPTMnet Report for O15146 (MUSK)
Protein Information
| UniProt AC / UniProt ID | O15146 / MUSK_HUMAN |
| Protein Name | Muscle, skeletal receptor tyrosine-protein kinase precursor |
| Gene Name | Name: MUSK |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O15146 |
| PRO Name | muscle, skeletal receptor tyrosine-protein kinase (human) |
| Definition | A muscle, skeletal receptor tyrosine-protein kinase that is encoded in the genome of human. |
| Short Label | hMUSK |
| Category | organism-gene |
DAG ViewO15146 (MUSK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y554 | Phosphorylation | score4 | neXtProt PhosphoSitePlus | 19244212, 16794080, 10781064 | ||
| Y577 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S681 | Phosphorylation | score2 | neXtProt | 16818610 | ||
| S698 | Phosphorylation | score2 | neXtProt | 16818610 | ||
| Y751 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y755 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y756 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y813 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S424 | F424 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S424 | Y424 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S430 | F430 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S681 | N681 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S681 | G681 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
