Protein Information

Cytoscape View


UniProt AC / UniProt ID O15146 / MUSK_HUMAN
Protein Name Muscle, skeletal receptor tyrosine-protein kinase precursor
Gene Name Name: MUSK
Organism Homo sapiens (Human)

PRO ID PR:O15146
DAG View
PRO Name muscle, skeletal receptor tyrosine-protein kinase (human)
Definition A muscle, skeletal receptor tyrosine-protein kinase that is encoded in the genome of human.
Short Label hMUSK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15146 (MUSK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
Y554 Phosphorylation neXtProt   PhosphoSitePlus 19244212, 16794080, 10781064
Y577 Phosphorylation PhosphoSitePlus
S681 Phosphorylation neXtProt 16818610
S698 Phosphorylation neXtProt 16818610
Y751 Phosphorylation PhosphoSitePlus
Y755 Phosphorylation PhosphoSitePlus
Y756 Phosphorylation PhosphoSitePlus
Y813 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S424 Y424 Biomuta DOID:1324 / lung cancer [ tcga ]
S681 N681 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S681 G681 Biomuta DOID:363 / uterine cancer [ tcga ]