iPTMnet Report for O14640 (DVL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14640 / DVL1_HUMAN
Protein Name Segment polarity protein dishevelled homolog DVL-1
Gene Name Name: DVL1
Organism Homo sapiens (Human)

PRO ID PR:O14640
DAG View
PRO Name segment polarity protein dishevelled homolog DVL-1 (human)
Definition A segment polarity protein dishevelled homolog DVL-1 that is encoded in the genome of human.
Short Label hDVL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14640 (DVL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
Ubiquitination PRO
Y8 Phosphorylation PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
K69 Acetylation PhosphoSitePlus
C72 Methylation IEDB 31844290
S79 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S139 Phosphorylation P49674 (CSNK1E) Signor 16965538
S142 Phosphorylation P49674 (CSNK1E) Signor 16965538
S188 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K476 Acetylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
R626 Methylation PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
T674 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S93 Phosphorylation HPRD 18077418


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047222 (hDVL1/PhosRes+) p PRO
PR:000047223 (hDVL1/PhosSer+) p PRO
PR:000047224 (hDVL1/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y8 C8 Biomuta DOID:363 / uterine cancer [ icgc ]
S139 F139 Biomuta DOID:4159 / skin cancer [ cosmic ]
K469 E469 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S604 L604 Biomuta DOID:1319 / brain cancer [ icgc ]
R626 C626 Biomuta DOID:4159 / skin cancer [ cosmic ]