iPTMnet Report for O14640 (DVL1)
Protein Information
UniProt AC / UniProt ID | O14640 / DVL1_HUMAN |
Protein Name | Segment polarity protein dishevelled homolog DVL-1 |
Gene Name | Name: DVL1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14640 |
PRO Name | segment polarity protein dishevelled homolog DVL-1 (human) |
Definition | A segment polarity protein dishevelled homolog DVL-1 that is encoded in the genome of human. |
Short Label | hDVL1 |
Category | organism-gene |
O14640 (DVL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
Ubiquitination | score1 | PRO | ||||
Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y17 | Phosphorylation | score1 | PhosphoSitePlus | |||
K34 | Acetylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
K69 | Acetylation | score1 | PhosphoSitePlus | |||
C72 | Methylation | score1 | IEDB | 31844290 | ||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
T100 | Phosphorylation | score1 | PhosphoSitePlus | |||
T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S139 | Phosphorylation | score1 | Signor | 16965538 | ||
S139 | Phosphorylation | P49674 (CSNK1E) | score1 | Signor | 16965538 | |
S142 | Phosphorylation | score1 | Signor | 16965538 | ||
S142 | Phosphorylation | P49674 (CSNK1E) | score1 | Signor | 16965538 | |
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K285 | Acetylation | score1 | PhosphoSitePlus | |||
K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
K469 | Ubiquitination | score1 | PhosphoSitePlus | |||
K476 | Acetylation | score1 | PhosphoSitePlus | |||
S600 | Phosphorylation | score1 | PhosphoSitePlus | |||
S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
S604 | Phosphorylation | score1 | PhosphoSitePlus | |||
S625 | Phosphorylation | score1 | PhosphoSitePlus | |||
R626 | Methylation | score1 | PhosphoSitePlus | |||
Y651 | Phosphorylation | score1 | PhosphoSitePlus | |||
T674 | Phosphorylation | score1 | PhosphoSitePlus | |||
S676 | Phosphorylation | score1 | PhosphoSitePlus | |||
S679 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000047222 (hDVL1/PhosRes+) | p | PRO | |||
PR:000047223 (hDVL1/PhosSer+) | p | PRO | |||
PR:000047224 (hDVL1/UbiqLys+) | ub | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y8 | C8 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S139 | F139 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K469 | E469 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S604 | L604 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
R626 | C626 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |