iPTMnet Report for O14639 (ABLIM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14639 / ABLM1_HUMAN
Protein Name Actin-binding LIM protein 1
Gene Name Name: ABLIM1
Synonyms:ABLIM,KIAA0059,LIMAB1;
Organism Homo sapiens (Human)

PRO ID PR:O14639
DAG View
PRO Name actin-binding LIM protein 1 (human)
Definition An actin-binding LIM protein 1 that is encoded in the genome of human.
Short Label hABLIM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14639 (ABLIM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T22 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S214 Phosphorylation RLIMS-P 33061800
S215 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
T351 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
T351 Phosphorylation PhosphoSitePlus
S352 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S352 Phosphorylation PhosphoSitePlus
S353 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S355 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation phospho.ELM   PhosphoSitePlus 15144186
S358 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S358 Phosphorylation PhosphoSitePlus
S362 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S362 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S363 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S363 Phosphorylation PhosphoSitePlus
S367 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T371 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
T371 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19690332, 15144186
Y383 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
Y396 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455
T405 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
Y410 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
T411 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
Y414 Phosphorylation PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus   UniProt 23186163
S426 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
T429 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
T429 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S431 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18088087, 33061800, 15302935, ...15144186, 18669648, 23186163, 19690332
T433 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S435 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15144186, ...18669648, 24275569, 19690332, 20068231
Y439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15144186
S450 O-Glycosylation GlyGen 34846842, 30059200, 28657654, ...29351928, 28580691, 35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 31373491, 29237092, 20068230
S450 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T451 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
T451 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S452 O-Glycosylation GlyGen   PhosphoSitePlus 34846842, 30059200, 28657654, ...29351928, 28580691, 35132862, 30620550, 8344946, 31492838, 29485866, 35289036, 35254053, 31373491, 29237092, 20068230
S452 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 15302935, ...15144186, 18669648
S455 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S455 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S458 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S458 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648
Y461 Phosphorylation phospho.ELM   PhosphoSitePlus 15144186, 16094384
S462 O-Glycosylation GlyGen 30059200, 28657654, 29351928, ...28580691, 35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 31373491, 29237092, 20068230
S462 Phosphorylation PhosphoSitePlus
S465 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S465 Phosphorylation PhosphoSitePlus
Y466 Phosphorylation PhosphoSitePlus
T467 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S471 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
T502 Phosphorylation PhosphoSitePlus
Y505 Phosphorylation PhosphoSitePlus
Y522 Phosphorylation PhosphoSitePlus
Y528 Phosphorylation PhosphoSitePlus
K529 Methylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
S587 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S631 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
Y638 Phosphorylation PhosphoSitePlus
S640 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S644 Phosphorylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
S651 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S651 Phosphorylation PhosphoSitePlus
K652 Ubiquitination PhosphoSitePlus
S655 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163
Y659 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
T670 Phosphorylation PhosphoSitePlus
Y675 Phosphorylation PhosphoSitePlus
S677 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
S677 Phosphorylation PhosphoSitePlus
Y678 Phosphorylation PhosphoSitePlus
S682 O-Glycosylation GlyGen 30059200, 29351928, 28580691, ...35132862, 30620550, 31492838, 29485866, 35289036, 35254053, 28657654, 29237092, 20068230
Y688 Phosphorylation PhosphoSitePlus
T690 Phosphorylation PhosphoSitePlus
S706 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 24275569
Y718 Phosphorylation PhosphoSitePlus
T724 Phosphorylation PhosphoSitePlus
R726 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S215 Phosphorylation HPRD 19664995
S352 Phosphorylation HPRD 17081983
S353 Phosphorylation HPRD 18669648
S355 Phosphorylation HPRD 17081983
Y357 Phosphorylation HPRD 19901323, 15144186
S362 Phosphorylation HPRD 18669648, 17081983
S363 Phosphorylation HPRD 17081983
S367 Phosphorylation HPRD 18669648, 20068231
Y373 Phosphorylation HPRD 19901323, 15144186
Y396 Phosphorylation HPRD 15592455
Y406 Phosphorylation HPRD 15592455
Y410 Phosphorylation HPRD 15592455
Y414 Phosphorylation HPRD 15592455
S422 Phosphorylation HPRD 20068231
S426 Phosphorylation HPRD 18669648, 20068231
T429 Phosphorylation HPRD 19413330, 20166139, 19664995, ...20068231
S431 Phosphorylation HPRD 19413330, 18088087, 18767875, ...19664994, 19664995, 18452278, 17322306, 18669648, 20058876, 20166139, 20068231
T433 Phosphorylation HPRD 18669648, 19664995, 20068231
S435 Phosphorylation HPRD 19413330, 19664995, 15144186, ...18452278, 18669648, 20166139, 20068231
Y439 Phosphorylation HPRD 19413330, 15144186, 19664995, ...20068231
S450 Phosphorylation HPRD 20166139, 18669648, 19664995, ...20068231
T451 Phosphorylation HPRD 20166139, 18669648
S452 Phosphorylation HPRD 19562805, 18767875, 18077418, ...15302935, 19664995, 15144186, 18669648, 20166139, 20068231
S455 Phosphorylation HPRD 20166139, 18669648
S458 Phosphorylation HPRD 18077418, 17525332, 18669648
Y461 Phosphorylation HPRD 15144186
S586 Phosphorylation HPRD 20166139, 18452278
S587 Phosphorylation HPRD 20166139, 18669648, 20068231
Y638 Phosphorylation HPRD 20068231
S640 Phosphorylation HPRD 18669648, 20068231
S651 Phosphorylation HPRD 20068231
S655 Phosphorylation HPRD 19413330, 18212344, 18767875, ...19664994, 19664995, 17322306, 18669648
S706 Phosphorylation HPRD 18212344, 18767875, 20058876, ...19664995, 17322306, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S155 Phosphorylation HPRD 19664995
S292 Phosphorylation HPRD 17081983
S293 Phosphorylation HPRD 18669648
S295 Phosphorylation HPRD 17081983
Y297 Phosphorylation HPRD 19901323
S302 Phosphorylation HPRD 18669648, 17081983
S303 Phosphorylation HPRD 17081983
S307 Phosphorylation HPRD 18669648, 20068231
Y313 Phosphorylation HPRD 19901323
Y336 Phosphorylation HPRD 15592455
Y346 Phosphorylation HPRD 15592455
Y350 Phosphorylation HPRD 15592455
Y354 Phosphorylation HPRD 15592455
S362 Phosphorylation HPRD 20068231
S366 Phosphorylation HPRD 18669648, 20068231
T369 Phosphorylation HPRD 19413330, 20166139, 19664995, ...20068231
S371 Phosphorylation HPRD 19413330, 18088087, 18767875, ...15570572, 19664995, 18452278, 19664994, 18669648, 20058876, 20166139, 20068231
T373 Phosphorylation HPRD 18669648, 19664995, 20068231
S375 Phosphorylation HPRD 19413330, 15570572, 19664995, ...18452278, 18669648, 20166139, 20068231
Y379 Phosphorylation HPRD 19413330, 19664995, 20068231
S390 Phosphorylation HPRD 20166139, 18669648, 19664995, ...20068231
T391 Phosphorylation HPRD 20166139, 18669648
S392 Phosphorylation HPRD 17525332, 19562805, 18767875, ...18077418, 19664995, 18669648, 20166139, 20068231
S395 Phosphorylation HPRD 20166139, 18669648
S398 Phosphorylation HPRD 18077418, 17525332, 18669648
S526 Phosphorylation HPRD 20166139, 18452278
S527 Phosphorylation HPRD 20166139, 18669648, 20068231
Y578 Phosphorylation HPRD 20068231
S580 Phosphorylation HPRD 18669648, 20068231
S591 Phosphorylation HPRD 20068231
S595 Phosphorylation HPRD 19413330, 18212344, 18767875, ...19664994, 19664995, 17322306, 18669648
S646 Phosphorylation HPRD 18212344, 18767875, 20058876, ...19664995, 17322306, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
Y44 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S65 Phosphorylation HPRD   PhosphoSitePlus 18669648
Y69 Phosphorylation HPRD   PhosphoSitePlus 19901323
S74 Phosphorylation HPRD 18669648
S79 Phosphorylation HPRD 18669648, 20068231
Y85 Phosphorylation HPRD   PhosphoSitePlus 19901323
Y95 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation HPRD   PhosphoSitePlus 15592455
Y118 Phosphorylation HPRD   PhosphoSitePlus 15592455
Y122 Phosphorylation HPRD   PhosphoSitePlus 15592455
Y126 Phosphorylation HPRD   PhosphoSitePlus 15592455
S134 Phosphorylation HPRD 20068231
S138 Phosphorylation HPRD 18669648, 20068231
T141 Phosphorylation HPRD 19413330, 20166139, 19664995, ...20068231
S143 Phosphorylation HPRD 19413330, 18088087, 18767875, ...15570572, 19664995, 18452278, 19664994, 18669648, 20058876, 20166139, 20068231
T145 Phosphorylation HPRD 18669648, 19664995, 20068231
S147 Phosphorylation HPRD 19413330, 15570572, 19664995, ...18452278, 18669648, 20166139, 20068231
Y151 Phosphorylation HPRD   PhosphoSitePlus 19413330, 19664995, 20068231
S162 Phosphorylation HPRD 20166139, 18669648, 19664995, ...20068231
T163 Phosphorylation HPRD 20166139, 18669648
S164 Phosphorylation HPRD 17525332, 19562805, 18767875, ...18077418, 19664995, 18669648, 20166139, 20068231
S167 Phosphorylation HPRD 20166139, 18669648
S170 Phosphorylation HPRD 18077418, 17525332, 18669648
Y173 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S185 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
Y199 Phosphorylation PhosphoSitePlus
S263 Phosphorylation HPRD 20166139, 18452278
S264 Phosphorylation HPRD   PhosphoSitePlus 20166139, 18669648, 20068231
Y315 Phosphorylation HPRD 20068231
S317 Phosphorylation HPRD 18669648, 20068231
S328 Phosphorylation HPRD 20068231
S332 Phosphorylation HPRD 19413330, 18212344, 18767875, ...19664994, 19664995, 17322306, 18669648
S383 Phosphorylation HPRD 18212344, 18767875, 20058876, ...19664995, 17322306, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 I28 Biomuta DOID:1324 / lung cancer [ cosmic ]
S45 Y45 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S45 F45 Biomuta DOID:4159 / skin cancer [ cosmic ]
S65 L65 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S79 L79 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y126 N126 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S138 F138 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y151 H151 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y151 C151 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S170 F170 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S214 L214 Biomuta DOID:4159 / skin cancer [ cosmic ]
S293 L293 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S295 I295 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S295 R295 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S303 R303 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S307 L307 Biomuta DOID:4159 / skin cancer [ cosmic ]
K345 R345 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T349 S349 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S353 L353 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y354 N354 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S355 R355 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S355 I355 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S358 C358 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S363 R363 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S366 F366 Biomuta DOID:4159 / skin cancer [ cosmic ]
S367 L367 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y379 C379 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y379 H379 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S398 F398 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y414 N414 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S426 F426 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y439 H439 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y439 C439 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S458 F458 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S471 F471 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S540 P540 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S632 F632 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S636 I636 Biomuta DOID:184 / bone cancer [ cosmic ]
S646 L646 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T670 N670 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y718 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R726 I726 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R726 K726 Biomuta DOID:4159 / skin cancer [ cosmic ]