iPTMnet Report for O14639 (ABLIM1)
Protein Information
UniProt AC / UniProt ID | O14639 / ABLM1_HUMAN |
Protein Name | Actin-binding LIM protein 1 |
Gene Name | Name: ABLIM1 Synonyms:ABLIM,KIAA0059,LIMAB1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14639 |
PRO Name | actin-binding LIM protein 1 (human) |
Definition | An actin-binding LIM protein 1 that is encoded in the genome of human. |
Short Label | hABLIM1 |
Category | organism-gene |
O14639 (ABLIM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
T349 | Phosphorylation | score1 | PhosphoSitePlus | |||
T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y357 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15144186 | ||
S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S363 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
T371 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y373 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19690332, 15144186 | ||
Y383 | Phosphorylation | score1 | PhosphoSitePlus | |||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y396 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y406 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15592455 | ||
Y410 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15592455 | ||
T411 | Phosphorylation | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y414 | Phosphorylation | score1 | PhosphoSitePlus | |||
K417 | Ubiquitination | score1 | PhosphoSitePlus | |||
S422 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S426 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 24275569 | ||
T429 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
S431 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18088087, 15302935, 15144186, ... | ||
T433 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
S435 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 15144186, ... | ||
Y439 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15144186 | ||
S450 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T451 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S452 | O-Glycosylation | score1 | PhosphoSitePlus | |||
S452 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 15302935, ... | ||
S455 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 24275569 | ||
S458 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 18669648 | ||
Y461 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15144186, 16094384 | ||
S462 | Phosphorylation | score1 | PhosphoSitePlus | |||
S465 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y466 | Phosphorylation | score1 | PhosphoSitePlus | |||
T467 | Phosphorylation | score1 | PhosphoSitePlus | |||
T469 | Phosphorylation | score1 | PhosphoSitePlus | |||
T502 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y505 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y522 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y528 | Phosphorylation | score1 | PhosphoSitePlus | |||
K529 | Methylation | score1 | PhosphoSitePlus | |||
K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
S538 | Phosphorylation | score1 | PhosphoSitePlus | |||
S540 | Phosphorylation | score1 | PhosphoSitePlus | |||
S541 | Phosphorylation | score1 | PhosphoSitePlus | |||
K546 | Ubiquitination | score1 | PhosphoSitePlus | |||
K549 | Ubiquitination | score1 | PhosphoSitePlus | |||
S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
S587 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S631 | Phosphorylation | score1 | PhosphoSitePlus | |||
S632 | Phosphorylation | score1 | PhosphoSitePlus | |||
S636 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y638 | Phosphorylation | score1 | PhosphoSitePlus | |||
S640 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
S644 | Phosphorylation | score1 | PhosphoSitePlus | |||
S646 | Phosphorylation | score1 | PhosphoSitePlus | |||
S651 | Phosphorylation | score1 | PhosphoSitePlus | |||
K652 | Ubiquitination | score1 | PhosphoSitePlus | |||
S655 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18669648, 15302935 | ||
Y659 | Phosphorylation | score1 | PhosphoSitePlus | |||
S669 | Phosphorylation | score1 | PhosphoSitePlus | |||
T670 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y675 | Phosphorylation | score1 | PhosphoSitePlus | |||
S677 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y678 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y688 | Phosphorylation | score1 | PhosphoSitePlus | |||
T690 | Phosphorylation | score1 | PhosphoSitePlus | |||
S706 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 15302935, 24275569 | ||
Y718 | Phosphorylation | score1 | PhosphoSitePlus | |||
T724 | Phosphorylation | score1 | PhosphoSitePlus | |||
R726 | Methylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S215 | Phosphorylation | score0 | HPRD | 19664995 | ||
S352 | Phosphorylation | score0 | HPRD | 17081983 | ||
S353 | Phosphorylation | score0 | HPRD | 18669648 | ||
S355 | Phosphorylation | score0 | HPRD | 17081983 | ||
Y357 | Phosphorylation | score0 | HPRD | 19901323, 15144186 | ||
S362 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S363 | Phosphorylation | score0 | HPRD | 17081983 | ||
S367 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
Y373 | Phosphorylation | score0 | HPRD | 19901323, 15144186 | ||
Y396 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y406 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y410 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y414 | Phosphorylation | score0 | HPRD | 15592455 | ||
S422 | Phosphorylation | score0 | HPRD | 20068231 | ||
S426 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T429 | Phosphorylation | score0 | HPRD | 19413330, 20166139, 19664995, ... | ||
S431 | Phosphorylation | score0 | HPRD | 19413330, 18088087, 18767875, ... | ||
T433 | Phosphorylation | score0 | HPRD | 18669648, 19664995, 20068231 | ||
S435 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 15144186, ... | ||
Y439 | Phosphorylation | score0 | HPRD | 19413330, 15144186, 19664995, ... | ||
S450 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 19664995, ... | ||
T451 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S452 | Phosphorylation | score0 | HPRD | 19562805, 18767875, 18077418, ... | ||
S455 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S458 | Phosphorylation | score0 | HPRD | 18077418, 17525332, 18669648 | ||
Y461 | Phosphorylation | score0 | HPRD | 15144186 | ||
S586 | Phosphorylation | score0 | HPRD | 20166139, 18452278 | ||
S587 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 | ||
Y638 | Phosphorylation | score0 | HPRD | 20068231 | ||
S640 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S651 | Phosphorylation | score0 | HPRD | 20068231 | ||
S655 | Phosphorylation | score0 | HPRD | 19413330, 18212344, 18767875, ... | ||
S706 | Phosphorylation | score0 | HPRD | 18212344, 18767875, 20058876, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S155 | Phosphorylation | score0 | HPRD | 19664995 | ||
S292 | Phosphorylation | score0 | HPRD | 17081983 | ||
S293 | Phosphorylation | score0 | HPRD | 18669648 | ||
S295 | Phosphorylation | score0 | HPRD | 17081983 | ||
Y297 | Phosphorylation | score0 | HPRD | 19901323 | ||
S302 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S303 | Phosphorylation | score0 | HPRD | 17081983 | ||
S307 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
Y313 | Phosphorylation | score0 | HPRD | 19901323 | ||
Y336 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y346 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y350 | Phosphorylation | score0 | HPRD | 15592455 | ||
Y354 | Phosphorylation | score0 | HPRD | 15592455 | ||
S362 | Phosphorylation | score0 | HPRD | 20068231 | ||
S366 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T369 | Phosphorylation | score0 | HPRD | 19413330, 20166139, 19664995, ... | ||
S371 | Phosphorylation | score0 | HPRD | 19413330, 18088087, 18767875, ... | ||
T373 | Phosphorylation | score0 | HPRD | 18669648, 19664995, 20068231 | ||
S375 | Phosphorylation | score0 | HPRD | 19413330, 15570572, 19664995, ... | ||
Y379 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 | ||
S390 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 19664995, ... | ||
T391 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S392 | Phosphorylation | score0 | HPRD | 17525332, 19562805, 18767875, ... | ||
S395 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S398 | Phosphorylation | score0 | HPRD | 18077418, 17525332, 18669648 | ||
S526 | Phosphorylation | score0 | HPRD | 20166139, 18452278 | ||
S527 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 | ||
Y578 | Phosphorylation | score0 | HPRD | 20068231 | ||
S580 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S591 | Phosphorylation | score0 | HPRD | 20068231 | ||
S595 | Phosphorylation | score0 | HPRD | 19413330, 18212344, 18767875, ... | ||
S646 | Phosphorylation | score0 | HPRD | 18212344, 18767875, 20058876, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y44 | Phosphorylation | score1 | PhosphoSitePlus | |||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S65 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648 | ||
Y69 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19901323 | ||
S74 | Phosphorylation | score0 | HPRD | 18669648 | ||
S79 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
Y85 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19901323 | ||
Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y108 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
Y118 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
Y122 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
Y126 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
S134 | Phosphorylation | score0 | HPRD | 20068231 | ||
S138 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T141 | Phosphorylation | score0 | HPRD | 19413330, 20166139, 19664995, ... | ||
S143 | Phosphorylation | score0 | HPRD | 19413330, 18088087, 18767875, ... | ||
T145 | Phosphorylation | score0 | HPRD | 18669648, 19664995, 20068231 | ||
S147 | Phosphorylation | score0 | HPRD | 19413330, 15570572, 19664995, ... | ||
Y151 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330, 19664995, 20068231 | ||
S162 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 19664995, ... | ||
T163 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S164 | Phosphorylation | score0 | HPRD | 17525332, 19562805, 18767875, ... | ||
S167 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S170 | Phosphorylation | score0 | HPRD | 18077418, 17525332, 18669648 | ||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
T179 | Phosphorylation | score1 | PhosphoSitePlus | |||
T181 | Phosphorylation | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983, 20068231 | ||
Y199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S263 | Phosphorylation | score0 | HPRD | 20166139, 18452278 | ||
S264 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139, 18669648, 20068231 | ||
Y315 | Phosphorylation | score0 | HPRD | 20068231 | ||
S317 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S328 | Phosphorylation | score0 | HPRD | 20068231 | ||
S332 | Phosphorylation | score0 | HPRD | 19413330, 18212344, 18767875, ... | ||
S383 | Phosphorylation | score0 | HPRD | 18212344, 18767875, 20058876, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K345 | R345 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
T349 | S349 | Biomuta | DOID:2394 / ovarian cancer [ icgc ] DOID:2994 / germ cell cancer [ cosmic ] | |
S358 | Y358 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
Y414 | N414 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y439 | H439 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y439 | C439 | Biomuta | DOID:11934 / head and neck cancer [ tcga ] | |
S458 | F458 | Biomuta | DOID:1909 / melanoma [ icgc, tcga ] | |
S540 | P540 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
K546 | T546 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
S632 | F632 | Biomuta | DOID:1793 / pancreatic cancer [ tcga ] | |
S636 | I636 | Biomuta | DOID:3371 / chondrosarcoma [ cosmic ] | |
S651 | F651 | Biomuta | DOID:3953 / adrenal gland cancer [ tcga ] | |
T670 | N670 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
Y718 | * | Biomuta | DOID:5041 / esophageal cancer [ icgc ] |