iPTMnet Report for O14607 (UTY)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14607 / UTY_HUMAN
Protein Name Histone demethylase UTY
Gene Name Name: UTY
Synonyms:KDM6C;
Organism Homo sapiens (Human)

PRO ID PR:O14607
DAG View
PRO Name histone demethylase UTY (human)
Definition A histone demethylase UTY that is encoded in the genome of human.
Short Label hUTY
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14607 (UTY) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
S486 O-Glycosylation GlyGen 32938750
S501 Phosphorylation PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
T679 Phosphorylation PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
K746 Acetylation PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
T887 Phosphorylation UniProt 24798337
K911 Ubiquitination PhosphoSitePlus
K965 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
T1033 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation PhosphoSitePlus
K1041 Ubiquitination PhosphoSitePlus
K1044 Ubiquitination PhosphoSitePlus
K1052 Ubiquitination PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
S1213 Phosphorylation PhosphoSitePlus
S1231 Phosphorylation PhosphoSitePlus
K1234 Ubiquitination PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T1033 Phosphorylation HPRD 18491316
S1038 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T1033 Phosphorylation HPRD 18491316
S1038 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
K392 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K392 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S501 R501 Biomuta DOID:4159 / skin cancer [ cosmic ]
S586 F586 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T1033 I1033 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1052 R1052 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1231 * Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K1248 E1248 Biomuta DOID:1612 / breast cancer [ cosmic ]