Protein Information

Cytoscape View

UniProt AC / UniProt ID O14493 / CLD4_HUMAN
Protein Name Claudin-4
Gene Name Name: CLDN4
Organism Homo sapiens (Human)

PRO ID PR:O14493
DAG View
PRO Name claudin-4 (human)
Definition A claudin-4 that is encoded in the genome of human.
Short Label hCLDN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O14493 (CLDN4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T189 Phosphorylation RLIMS-P 17678893
Y193 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus   RLIMS-P 17678893, 18786529
S194 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 18786529
Y197 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16236711
Y208 Phosphorylation P29317 (EPHA2) neXtProt   phospho.ELM   PhosphoSitePlus 16236711

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S194 F194 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S198 P198 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]