iPTMnet Report for O14493 (CLDN4)
Protein Information
| UniProt AC / UniProt ID | O14493 / CLD4_HUMAN |
| Protein Name | Claudin-4 |
| Gene Name | Name: CLDN4 Synonyms:CPER; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O14493 |
| PRO Name | claudin-4 (human) |
| Definition | A claudin-4 that is encoded in the genome of human. |
| Short Label | hCLDN4 |
| Category | organism-gene |
DAG ViewO14493 (CLDN4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T189 | Phosphorylation | score0 | RLIMS-P | 17678893 | ||
| Y193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S194 | Phosphorylation | P17252 (PRKCA) | score4 | PhosphoSitePlus RLIMS-P | 17678893, 18786529 | |
| Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y208 | Phosphorylation | P29317 (EPHA2) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 16236711, 33172177 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S194 | F194 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S198 | P198 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
