iPTMnet Report for O00763 (ACACB)
Protein Information
UniProt AC / UniProt ID | O00763 / ACACB_HUMAN |
Protein Name | Acetyl-CoA carboxylase 2 precursor |
Gene Name | Name: ACACB Synonyms:ACC2,ACCB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00763 |
PRO Name | acetyl-CoA carboxylase 2 (human) |
Definition | An acetyl-CoA carboxylase 2 that is encoded in the genome of human. |
Short Label | hACACB |
Category | organism-gene |
O00763 (ACACB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S35 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T70 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S91 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S95 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S200 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S222 | Phosphorylation | Q13131 (PRKAA1) , P54646 (PRKAA2) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 14613924, 12488245, 19900410, ... | |
S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
K454 | Acetylation | score1 | PhosphoSitePlus | |||
S469 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K663 | Ubiquitination | score1 | PhosphoSitePlus | |||
C703 | Methylation | score1 | IEDB | 31844290 | ||
K722 | Ubiquitination | score1 | PhosphoSitePlus | |||
S808 | Phosphorylation | score1 | PhosphoSitePlus | |||
S865 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y866 | Phosphorylation | score1 | PhosphoSitePlus | |||
T895 | Phosphorylation | score1 | PhosphoSitePlus | |||
C1077 | Methylation | score1 | IEDB | 31844290 | ||
S1340 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1342 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S1350 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1351 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1413 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1414 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1450 | Acetylation | score1 | PhosphoSitePlus | |||
Y1456 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1473 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1489 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1557 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1560 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1641 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1658 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1664 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1826 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1831 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y2327 | Phosphorylation | score1 | IEDB | 35494241 | ||
S2347 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2458 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S91 | F91 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S95 | F95 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S200 | F200 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S200 | C200 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S469 | I469 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K663 | E663 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
S865 | N865 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S1350 | I1350 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S1350 | R1350 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S1557 | F1557 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1831 | N1831 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
T2458 | I2458 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |