iPTMnet Report O00571 DDX3X

Protein Information

UniProt AC / UniProt ID	O00571 / DDX3X_HUMAN
Protein Name	ATP-dependent RNA helicase DDX3X
Gene Name	Name: DDX3X Synonyms:DBX;
Organism	Homo sapiens (Human)

PRO ID	PR:O00571 DAG View
PRO Name	ATP-dependent RNA helicase DDX3X (human)
Definition	An ATP-dependent RNA helicase DDX3X that is encoded in the genome of human.
Short Label	hDDX3X
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

O00571 (DDX3X) as Substrate

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S2 S24 K50 Y53 K55 S61 S62 S63 K64 K66 Y69 S70 S71 S74 R75 S76 S78 R79 K81 S82 S83 S86 R88 S90 S92 R93 R95 R99 R101 S102 Y104 S109 R110 S114 K118 R121 S125 K130 S131 K138 S152 T156 Y163 S181 S183 Y200 T204 K208 K215 K217 S228 K230 S240 Y243 Y260 K264 Y266 S269 Y283 Y301 R315 C317 T323 K335 K342 Y343 R362 K373 S410 K418 K427 S429 T438 S442 K452 S456 Y462 Y466 C468 T469 S470 R475 R478 S489 K491 S492 S508 K511 S520 T542 S543 K554 K564 Y576 Y580 K581 S584 R585 R587 S588 S590 S591 R592 S594 R600 Y602 R603 S605 S606 S609 S611 S612 S614 S615 S616 R617 S619 R622 R632 Y639 Y652	PTM Type Select all Acetylation Methylation O-Glycosylation Phosphorylation S-Nitrosylation Sumoylation Ubiquitination	PTM Enzyme	Score Select all 0 1 2 3 4	Source Select all GlyGen IEDB PhosphoSitePlus RLIMS-P Signor UniProt dbSNO neXtProt phospho.ELM	PMID
S2	Acetylation		score3	UniProt	22223895, 10859333, 20068231
S24	Phosphorylation		score1	PhosphoSitePlus
K50	Ubiquitination		score1	PhosphoSitePlus
Y53	Phosphorylation		score1	PhosphoSitePlus
K55	Ubiquitination		score1	PhosphoSitePlus
S61	Phosphorylation		score1	PhosphoSitePlus
S62	Phosphorylation		score1	PhosphoSitePlus
S63	Phosphorylation		score1	PhosphoSitePlus
K64	Ubiquitination		score1	PhosphoSitePlus
K66	Methylation		score1	PhosphoSitePlus
K66	Ubiquitination		score1	PhosphoSitePlus
Y69	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	15592455, 16094384
S70	Phosphorylation		score1	PhosphoSitePlus
S71	Phosphorylation		score1	PhosphoSitePlus
S74	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	14729942, 17287340
R75	Methylation		score1	PhosphoSitePlus
S76	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17287340
S78	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17287340
R79	Methylation		score1	PhosphoSitePlus
K81	Methylation		score1	PhosphoSitePlus
K81	Ubiquitination		score1	PhosphoSitePlus
S82	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S83	Phosphorylation		score1	PhosphoSitePlus
S86	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
R88	Methylation		score1	PhosphoSitePlus
S90	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S92	Phosphorylation		score1	PhosphoSitePlus
R93	Methylation		score1	PhosphoSitePlus
R95	Methylation		score1	PhosphoSitePlus
R99	Methylation		score1	PhosphoSitePlus
R101	Methylation		score1	PhosphoSitePlus
S102	Phosphorylation	Q14164 (IKBKE)	score3	PhosphoSitePlus RLIMS-P UniProt	23478265
Y104	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	15592455
S109	Phosphorylation		score1	PhosphoSitePlus
R110	Methylation		score1	PhosphoSitePlus
S114	O-Glycosylation		score1	GlyGen	33214551, 28510447, 32870666, ...30397120, 34725712, 26853435, 30444036, 29351928, 34019948, 35083852, 31492838, 32119511, 35254053, 33465208
S114	Phosphorylation		score1	PhosphoSitePlus
K118	Acetylation		score2	PhosphoSitePlus UniProt	19608861
K118	Methylation		score1	PhosphoSitePlus
K118	Sumoylation		score1	PhosphoSitePlus
K118	Ubiquitination		score1	PhosphoSitePlus
R121	Methylation		score1	PhosphoSitePlus
S125	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17287340
K130	Acetylation		score1	PhosphoSitePlus
K130	Ubiquitination		score1	PhosphoSitePlus
S131	Phosphorylation		score2	PhosphoSitePlus UniProt	21406692
K138	Methylation		score1	PhosphoSitePlus
K138	Sumoylation		score1	PhosphoSitePlus
K138	Ubiquitination		score1	PhosphoSitePlus
S152	Phosphorylation		score1	PhosphoSitePlus
T156	Phosphorylation		score1	PhosphoSitePlus
Y163	Phosphorylation		score1	PhosphoSitePlus
S181	Phosphorylation		score2	UniProt	18583960
S183	Phosphorylation		score4	PhosphoSitePlus UniProt	24275569, 18583960
Y200	Phosphorylation		score1	PhosphoSitePlus
T204	O-Glycosylation		score1	GlyGen	33214551, 28510447, 32870666, ...30397120, 34725712, 26853435, 30444036, 29351928, 34019948, 35083852, 31492838, 32119511, 35254053, 33465208
T204	Phosphorylation	P24941 (CDK2) , P06493 (CDK1)	score4	neXtProt phospho.ELM PhosphoSitePlus Signor	16280325, 17379183
K208	Ubiquitination		score1	PhosphoSitePlus
K215	Sumoylation		score1	PhosphoSitePlus
K215	Ubiquitination		score1	PhosphoSitePlus
K217	Ubiquitination		score1	PhosphoSitePlus
S228	Phosphorylation		score1	PhosphoSitePlus
K230	Ubiquitination		score1	PhosphoSitePlus
S240	Phosphorylation		score2	UniProt	18583960
Y243	Phosphorylation		score1	PhosphoSitePlus
Y260	Phosphorylation		score1	PhosphoSitePlus
K264	Ubiquitination		score1	PhosphoSitePlus
Y266	Phosphorylation		score1	PhosphoSitePlus
S269	Phosphorylation		score2	UniProt	18583960
Y283	Phosphorylation		score1	PhosphoSitePlus
Y301	Phosphorylation		score1	PhosphoSitePlus
R315	Methylation		score1	PhosphoSitePlus
C317	Methylation		score1	IEDB	31844290
C317	S-Nitrosylation		score0	dbSNO	2212679, 22126794
T323	Phosphorylation	P06493 (CDK1)	score4	phospho.ELM PhosphoSitePlus Signor	16280325, 17379183
K335	Ubiquitination		score1	PhosphoSitePlus
K342	Ubiquitination		score1	PhosphoSitePlus
Y343	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	16097034
R362	Methylation		score1	PhosphoSitePlus
K373	Ubiquitination		score1	PhosphoSitePlus
S410	Phosphorylation		score1	PhosphoSitePlus
K418	Ubiquitination		score1	PhosphoSitePlus
K427	Ubiquitination		score1	PhosphoSitePlus
S429	Phosphorylation		score4	PhosphoSitePlus RLIMS-P UniProt	18583960, 29222110
T438	Phosphorylation		score3	PhosphoSitePlus UniProt	18583960
S442	Phosphorylation		score2	UniProt	18583960
K452	Ubiquitination		score1	PhosphoSitePlus
S456	Phosphorylation		score3	PhosphoSitePlus UniProt	18583960
Y462	Phosphorylation		score1	PhosphoSitePlus
Y466	Phosphorylation		score1	PhosphoSitePlus
C468	Methylation		score1	IEDB	31844290
T469	Phosphorylation		score2	UniProt	29222110
S470	Phosphorylation		score2	UniProt	29222110
R475	Methylation		score1	PhosphoSitePlus
R478	Methylation		score1	PhosphoSitePlus
S489	Phosphorylation		score1	PhosphoSitePlus
K491	Ubiquitination		score1	PhosphoSitePlus
S492	Phosphorylation		score1	PhosphoSitePlus
S508	Phosphorylation		score1	PhosphoSitePlus
K511	Ubiquitination		score1	PhosphoSitePlus
S520	Phosphorylation		score3	PhosphoSitePlus UniProt	18583960
T542	Phosphorylation		score2	UniProt	18583960
S543	Phosphorylation		score4	PhosphoSitePlus RLIMS-P UniProt	18583960, 29222110
K554	Ubiquitination		score1	PhosphoSitePlus
K564	Ubiquitination		score1	PhosphoSitePlus
Y576	Phosphorylation		score1	PhosphoSitePlus
Y580	Phosphorylation		score1	PhosphoSitePlus
K581	Methylation		score1	PhosphoSitePlus
S584	O-Glycosylation		score1	GlyGen	33214551, 28510447, 32870666, ...30397120, 34725712, 26853435, 30444036, 29351928, 34019948, 35083852, 31492838, 32119511, 35254053, 33465208
R585	Methylation		score1	PhosphoSitePlus
R587	Methylation		score1	PhosphoSitePlus
S588	O-Glycosylation		score1	GlyGen	33214551, 28510447, 32870666, ...30397120, 34725712, 26853435, 30444036, 29351928, 34019948, 35083852, 31492838, 32119511, 35254053, 33465208
S590	Phosphorylation		score1	PhosphoSitePlus
S591	Phosphorylation		score1	PhosphoSitePlus
R592	Methylation		score2	PhosphoSitePlus UniProt	24129315
S594	Phosphorylation	Q96GD4 (AURKB)	score2	PhosphoSitePlus UniProt	22267324, 23186163
R600	Methylation		score1	PhosphoSitePlus
Y602	Phosphorylation		score1	PhosphoSitePlus
R603	Methylation		score1	PhosphoSitePlus
S605	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S606	Phosphorylation		score1	PhosphoSitePlus
S609	Phosphorylation		score1	PhosphoSitePlus
S611	O-Glycosylation		score1	GlyGen	30444036, 28510447, 32870666, ...30397120, 34725712, 26853435, 33214551, 29351928, 34019948, 35083852, 31492838, 31373491, 32119511, 35254053, 33465208
S611	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18669648
S612	Phosphorylation		score2	PhosphoSitePlus UniProt	18669648
S614	Phosphorylation		score1	PhosphoSitePlus
S615	O-Glycosylation		score1	GlyGen	31373491
S615	Phosphorylation		score1	PhosphoSitePlus
S616	O-Glycosylation		score1	GlyGen	33214551, 28510447, 32870666, ...30397120, 34725712, 26853435, 30444036, 30059200, 34019948, 35083852, 31492838, 35254053, 32119511, 29351928, 33465208
S616	Phosphorylation		score1	PhosphoSitePlus
R617	Methylation		score2	PhosphoSitePlus UniProt	24129315
S619	Phosphorylation		score1	PhosphoSitePlus
R622	Methylation		score1	PhosphoSitePlus
R632	Methylation		score2	PhosphoSitePlus UniProt	24129315
Y639	Phosphorylation		score1	PhosphoSitePlus
Y652	Phosphorylation		score1	PhosphoSitePlus

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S23 S57 S58 S61 S62 S63 Y69 S74 S76 S78 S82 S83 S92 S102 Y104 S125 T204 T323 Y343 S590 S594 S612	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
S23	Phosphorylation	score0	HPRD	20068231
S57	Phosphorylation	score0	HPRD	20068231
S58	Phosphorylation	score0	HPRD	20068231
S61	Phosphorylation	score0	HPRD	18669648, 20068231
S62	Phosphorylation	score0	HPRD	20068231
S63	Phosphorylation	score0	HPRD	20068231
Y69	Phosphorylation	score0	HPRD	19901323, 16094384
S74	Phosphorylation	score0	HPRD	14729942, 17287340
S76	Phosphorylation	score0	HPRD	17287340
S78	Phosphorylation	score0	HPRD	17287340
S82	Phosphorylation	score0	HPRD	18669648, 18212344
S83	Phosphorylation	score0	HPRD	18212344
S92	Phosphorylation	score0	HPRD	18669648
S102	Phosphorylation	score0	HPRD	18212344
Y104	Phosphorylation	score0	HPRD	15592455
S125	Phosphorylation	score0	HPRD	17287340
T204	Phosphorylation	score0	HPRD	20068231
T323	Phosphorylation	score0	HPRD	20068231
Y343	Phosphorylation	score0	HPRD	17924679
S590	Phosphorylation	score0	HPRD	17924679
S594	Phosphorylation	score0	HPRD	19413330, 18212344, 19691289, ...19664995, 18669648, 19415658, 20068231, 17924679
S612	Phosphorylation	score0	HPRD	18669648

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for O00571 (DDX3X)

Protein Information

Interactive Sequence View

O00571 (DDX3X) as Substrate