iPTMnet Report for O00232 (PSMD12)
Protein Information
UniProt AC / UniProt ID | O00232 / PSD12_HUMAN |
Protein Name | 26S proteasome non-ATPase regulatory subunit 12 |
Gene Name | Name: PSMD12 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00232 |
PRO Name | 26S proteasome non-ATPase regulatory subunit 12 (human) |
Definition | A 26S proteasome non-ATPase regulatory subunit 12 that is encoded in the genome of human. |
Short Label | hPSMD12 |
Category | organism-gene |
O00232 (PSMD12) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 12665801 | ||
Y20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K92 | Sumoylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y111 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y137 | Phosphorylation | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
K212 | Acetylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K221 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
C255 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K262 | Acetylation | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
S332 | Phosphorylation | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S343 | Phosphorylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
K368 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y369 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
K448 | Acetylation | score1 | PhosphoSitePlus | |||
K448 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | S2 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
Y207 | C207 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K212 | N212 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y227 | C227 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K262 | N262 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S434 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] |