iPTMnet Report for O00221 (NFKBIE)
Protein Information
| UniProt AC / UniProt ID | O00221 / IKBE_HUMAN |
| Protein Name | NF-kappa-B inhibitor epsilon |
| Gene Name | Name: NFKBIE Synonyms:IKBE; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00221 |
| PRO Name | NF-kappa-B inhibitor epsilon (human) |
| Definition | An NF-kappa-B inhibitor epsilon that is encoded in the genome of human. |
| Short Label | hNFKBIE |
| Category | organism-gene |
DAG ViewO00221 (NFKBIE) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S157 | Phosphorylation | score2 | PRO PhosphoSitePlus UniProt | 23186163 | ||
| S161 | Phosphorylation | score2 | PRO PhosphoSitePlus | |||
| S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S167 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S183 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C335 | Methylation | score1 | IEDB | 31844290 | ||
| C373 | Methylation | score1 | IEDB | 31844290 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048599 (hNFKBIE/Phos:1) | pS157,pS161 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S54 | F54 | Biomuta | [ cosmic ] | |
| Y155 | H155 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| Y155 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K316 | M316 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C373 | F373 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
