Protein Information

Cytoscape View


UniProt AC / UniProt ID O00221 / IKBE_HUMAN
Protein Name NF-kappa-B inhibitor epsilon
Gene Name Name: NFKBIE
Synonyms:IKBE;
Organism Homo sapiens (Human)

PRO ID PR:O00221
DAG View
PRO Name NF-kappa-B inhibitor epsilon (human)
Definition An NF-kappa-B inhibitor epsilon that is encoded in the genome of human.
Short Label hNFKBIE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00221 (NFKBIE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S54 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PRO   PhosphoSitePlus   UniProt 23186163
S161 Phosphorylation PRO   PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus   UniProt 23186163
K316 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048599 (hNFKBIE/Phos:1) pS157,pS161 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y155 H155 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K316 M316 Biomuta DOID:363 / uterine cancer [ tcga ]