iPTMnet Report for O00167 (EYA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00167 / EYA2_HUMAN
Protein Name Eyes absent homolog 2
Gene Name Name: EYA2
Synonyms:EAB1;
Organism Homo sapiens (Human)

PRO ID PR:O00167
DAG View
PRO Name eyes absent homolog 2 (human)
Definition An eyes absent homolog 2 that is encoded in the genome of human.
Short Label hEYA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00167 (EYA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S257 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
C441 Methylation IEDB 31844290
K480 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047342 (hEYA2/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K296 N296 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C441 G441 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K480 R480 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]