iPTMnet Report for O00167 (EYA2)
Protein Information
UniProt AC / UniProt ID | O00167 / EYA2_HUMAN |
Protein Name | Eyes absent homolog 2 |
Gene Name | Name: EYA2 Synonyms:EAB1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00167 |
PRO Name | eyes absent homolog 2 (human) |
Definition | An eyes absent homolog 2 that is encoded in the genome of human. |
Short Label | hEYA2 |
Category | organism-gene |
O00167 (EYA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
T404 | Phosphorylation | score1 | PhosphoSitePlus | |||
C441 | Methylation | score1 | IEDB | 31844290 | ||
K480 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K296 | N296 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
C441 | G441 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K480 | R480 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |