iPTMnet Report for A8K8P3 (SFI1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A8K8P3 / SFI1_HUMAN
Protein Name Protein SFI1 homolog
Gene Name Name: SFI1
Synonyms:KIAA0542;
Organism Homo sapiens (Human)

PRO ID PR:A8K8P3
DAG View
PRO Name protein SFI1 homolog (human)
Definition A protein SFI1 that is encoded in the genome of human.
Short Label hSFI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A8K8P3 (SFI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
C147 Methylation IEDB 31844290
Y152 Phosphorylation PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
T695 Phosphorylation PhosphoSitePlus
C717 Methylation IEDB 31844290
Y733 Phosphorylation PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
C753 Methylation IEDB 31844290
K795 Ubiquitination PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
K975 Ubiquitination PhosphoSitePlus
K1111 Ubiquitination PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1179 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S1148 Phosphorylation HPRD 17081983


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P41208 (CETN2) T138 A8K8P3 (SFI1) inhibited_association eFIP 24918055
Phosphorylation Q12798 (CETN1) T138 A8K8P3 (SFI1) decreased_association eFIP 24918055


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C753 R753 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1146 N1146 Biomuta DOID:10534 / stomach cancer [ cosmic ]