Protein Information

Cytoscape View

UniProt AC / UniProt ID A8K8P3 / SFI1_HUMAN
Protein Name Protein SFI1 homolog
Gene Name Name: SFI1
Organism Homo sapiens (Human)

DAG View
PRO Name protein SFI1 homolog (human)
Definition A protein SFI1 that is encoded in the genome of human.
Short Label hSFI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

A8K8P3 (SFI1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
T695 Phosphorylation PhosphoSitePlus
Y733 Phosphorylation PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
K795 Ubiquitination PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
K975 Ubiquitination PhosphoSitePlus
K1111 Ubiquitination PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1179 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S1148 Phosphorylation HPRD 17081983

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P41208 (CETN2) T138 A8K8P3 (SFI1) inhibited_association eFIP 24918055
Phosphorylation Q12798 (CETN1) T138 A8K8P3 (SFI1) decreased_association eFIP 24918055

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1146 I1146 Biomuta DOID:3571 / liver cancer [ icgc ]