iPTMnet Report for A7MCY6 (TBKBP1)
Protein Information
UniProt AC / UniProt ID | A7MCY6 / TBKB1_HUMAN |
Protein Name | TANK-binding kinase 1-binding protein 1 |
Gene Name | Name: TBKBP1 Synonyms:KIAA0775; |
Organism | Homo sapiens (Human) |
PRO ID | PR:A7MCY6 |
PRO Name | TANK-binding kinase 1-binding protein 1 (human) |
Definition | A TANK-binding kinase 1-binding protein 1 that is encoded in the genome of human. |
Short Label | hTBKBP1 |
Category | organism-gene |
A7MCY6 (TBKBP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y48 | Phosphorylation | score1 | PhosphoSitePlus | |||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S372 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S379 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S385 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
S400 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195, 24275569 | ||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S415 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
R427 | Methylation | score1 | IEDB | 32357974 | ||
T485 | Phosphorylation | score1 | PhosphoSitePlus | |||
S504 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195, 23186163 | ||
R513 | Methylation | score1 | PhosphoSitePlus | |||
S521 | Phosphorylation | score1 | PhosphoSitePlus | |||
S534 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T13 | M13 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] | |
S97 | F97 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K262 | N262 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S335 | P335 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S349 | P349 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S351 | P351 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S385 | P385 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |