Protein Information

Cytoscape View


UniProt AC / UniProt ID A7MCY6 / TBKB1_HUMAN
Protein Name TANK-binding kinase 1-binding protein 1
Gene Name Name: TBKBP1
Synonyms:KIAA0775;
Organism Homo sapiens (Human)

PRO ID PR:A7MCY6
DAG View
PRO Name TANK-binding kinase 1-binding protein 1 (human)
Definition A TANK-binding kinase 1-binding protein 1 that is encoded in the genome of human.
Short Label hTBKBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A7MCY6 (TBKBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus   UniProt 19369195
K262 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus   UniProt 19369195
S372 Phosphorylation PhosphoSitePlus   UniProt 19369195
S379 Phosphorylation PhosphoSitePlus   UniProt 19369195
S385 Phosphorylation PhosphoSitePlus   UniProt 19369195
S388 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus   UniProt 19369195, 24275569
S405 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus   UniProt 19369195
T485 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
R513 Methylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus   UniProt 19369195
Site PTM Type PTM Enzyme Score Source PMID
S372 Phosphorylation HPRD 19413330
S379 Phosphorylation HPRD 19413330
S400 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 I184 Biomuta DOID:3571 / liver cancer [ icgc ]
K262 N262 Biomuta DOID:363 / uterine cancer [ tcga ]
S349 P349 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S351 P351 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]