iPTMnet Report for A7MCY6 (TBKBP1)
Protein Information
| UniProt AC / UniProt ID | A7MCY6 / TBKB1_HUMAN |
| Protein Name | TANK-binding kinase 1-binding protein 1 |
| Gene Name | Name: TBKBP1 Synonyms:KIAA0775; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:A7MCY6 |
| PRO Name | TANK-binding kinase 1-binding protein 1 (human) |
| Definition | A TANK-binding kinase 1-binding protein 1 that is encoded in the genome of human. |
| Short Label | hTBKBP1 |
| Category | organism-gene |
A7MCY6 (TBKBP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| S372 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| S379 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| S385 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S400 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195, 24275569 | ||
| S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S415 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| R427 | Methylation | score1 | IEDB | 32357974 | ||
| T485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S504 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195, 23186163 | ||
| R513 | Methylation | score1 | PhosphoSitePlus | |||
| S521 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S534 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T13 | M13 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] | |
| S97 | F97 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K262 | N262 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S335 | P335 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S349 | P349 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S351 | P351 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S385 | P385 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View