iPTMnet Report for A2PYH4 (HFM1)
Protein Information
UniProt AC / UniProt ID | A2PYH4 / HFM1_HUMAN |
Protein Name | Probable ATP-dependent DNA helicase HFM1 |
Gene Name | Name: HFM1 Synonyms:SEC3D1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:A2PYH4 |
PRO Name | probable ATP-dependent DNA helicase HFM1 (human) |
Definition | A probable ATP-dependent DNA helicase HFM1 that is encoded in the genome of human. |
Short Label | hHFM1 |
Category | organism-gene |
A2PYH4 (HFM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
T393 | Phosphorylation | score1 | PhosphoSitePlus | |||
S545 | Phosphorylation | score1 | PhosphoSitePlus | |||
T556 | Phosphorylation | score1 | PhosphoSitePlus | |||
T670 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y798 | Phosphorylation | score1 | PhosphoSitePlus | |||
T799 | Phosphorylation | score1 | PhosphoSitePlus | |||
S807 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1053 | Acetylation | score1 | PhosphoSitePlus | |||
K1059 | Acetylation | score1 | PhosphoSitePlus | |||
T1112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1118 | Acetylation | score1 | PhosphoSitePlus | |||
S1123 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1130 | Acetylation | score1 | PhosphoSitePlus | |||
T1132 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1133 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1135 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1136 | Acetylation | score1 | PhosphoSitePlus | |||
S1171 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1172 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1307 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1323 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K65 | E65 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S807 | T807 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K1059 | E1059 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K1118 | E1118 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T1132 | K1132 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S1135 | T1135 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S1171 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |