Terms by PRO Category |
Retrieve All terms OBO Stanza
/ PAF
Organism-Specific |
Category |
Number of Terms |
organism-gene
|
1 |
organism-sequence
|
7 |
organism-modification
|
19 |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
|
hTGFB1 forms found in complexes |
|
Functional Annotation
|
PRO Term |
GO Annotation |
Evidence |
PR:000000620
hTGFB1/var:T81H/Clv:2
Tyr-81, CHEBI:29979
|
located_in |
GO:0005615 extracellular space
|
PMID:12493741 |
PR:000000621
hTGFB1/var:R218C/Clv:1
Arg-218, CHEBI:29950
|
capable_of |
GO:0042803 protein homodimerization activity
|
PMID:11062463, PMID:12493741, PMID:12843182 |
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000000616 TGFB1/iso:1/mature
|
PMID:11062463, PMID:12493741, PMID:12843182 |
capable_of |
GO:0005160 transforming growth factor beta receptor binding
|
PMID:11278244 |
located_in |
GO:0005615 extracellular space
|
PMID:11062463, PMID:12493741, PMID:12843182 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000622
hTGFB1/var:R218C/Clv:2
Arg-218, CHEBI:29950
|
has_agent |
SO:0001561 polypeptide_partial_loss_of_function
|
PMID:11278244 |
PR:000000623
hTGFB1/var:H222D/Clv:1
His-222, CHEBI:29958
|
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000000616 TGFB1/iso:1/mature
|
PMID:12493741 |
located_in |
GO:0005615 extracellular space
|
PMID:12493741 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:12493741 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:12493741 |
PR:000000624
hTGFB1/var:H222D/Clv:2
His-222, CHEBI:29958
|
has_agent |
SO:0001601 conformational_change_variant
|
PMID:11278244 |
has_agent |
SO:0001561 polypeptide_partial_loss_of_function
|
PMID:11278244 |
PR:000000625
hTGFB1/var:C225R/Clv:1
Cys-225, CHEBI:29952
|
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000000616 TGFB1/iso:1/mature
|
PMID:11062463, PMID:12493741, PMID:12843182 |
located_in |
GO:0005615 extracellular space
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000626
hTGFB1/var:C225R/Clv:2
Cys-225, CHEBI:29952
|
has_agent |
SO:0001561 polypeptide_partial_loss_of_function
|
PMID:11278244 |
PR:P01137-1
hTGFB1/iso:1
|
capable_of |
GO:0042803 protein homodimerization activity
|
PMID:1544940 |
located_in |
GO:0005796 Golgi lumen
|
PMID:1544940 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:9918798 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:1544940 |
PR:000000628
hTGFB1/var:R218H/Clv:2
Arg-218, CHEBI:29979
|
has_agent |
SO:0001561 polypeptide_partial_loss_of_function
|
PMID:11278244 |
has_agent |
SO:0001601 conformational_change_variant
|
PMID:11278244 |
PR:000000400
hTGFB1/var:R218C
Arg-218, CHEBI:29950
|
associated_with_disease_progression |
DOID:4997 Camurati-Engelmann disease
|
PMID:10973241, PMID:11062463, PMID:12493741, PMID:12843182 |
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000002555 TGFB1/iso:1/UnMod
|
PMID:11062463, PMID:12493741, PMID:12843182 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:12843182 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000401
hTGFB1/var:R218H
Arg-218, CHEBI:29979
|
associated_with_disease_progression |
DOID:4997 Camurati-Engelmann disease
|
PMID:12493741 |
PR:000000402
hTGFB1/var:H222D
His-222, CHEBI:29958
|
associated_with_disease_progression |
DOID:4997 Camurati-Engelmann disease
|
PMID:12493741 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:12493741 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:12493741 |
PR:000000403
hTGFB1/var:C225R
Cys-225, CHEBI:29952
|
associated_with_disease_progression |
DOID:4997 Camurati-Engelmann disease
|
PMID:12493741 |
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000002555 TGFB1/iso:1/UnMod
|
PMID:11062463, PMID:12493741, PMID:12843182 |
located_in |
GO:0005615 extracellular space
|
PMID:11062463, PMID:12493741, PMID:12843182 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:11062463, PMID:12493741, PMID:12843182 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000398
hTGFB1/var:L10P
Leu-10, CHEBI:50342
|
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:9783545 |
PR:000000399
hTGFB1/var:T81H
Tyr-81, CHEBI:29979
|
associated_with_disease_progression |
DOID:4997 Camurati-Engelmann disease
|
PMID:12493741 |
has_agent |
SO:0001558 polypeptide_localization_variant
|
PMID:11062463, PMID:12493741 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:11062463 |
PR:000026335
hTGFB1/iso:1/inactive
Asn-82, MOD:00160
|
capable_of |
NOT
GO:0005160 transforming growth factor beta receptor binding
|
PMID:2677679, PMID:3162913 |
capable_of |
GO:0042803 protein homodimerization activity
|
PMID:3162913 |
located_in |
GO:0031012 extracellular matrix
|
PMID:17015622, PMID:8294500 |
part_of |
GO:0032991 protein-containing complex
|
PMID:3162913 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:3162913 |
PR:000025927
hTGFB1/iso:1/mature
|
capable_of |
GO:0042803 protein homodimerization activity
|
PMID:3162913, PMID:8471846 |
located_in |
GO:0031012 extracellular matrix
|
PMID:8294500 |
participates_in |
GO:0043066 negative regulation of apoptotic process
|
PMID:9918798 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:8471846 |
PR:000036526
hTGFB1/iso:1/LAP
Asn-82, MOD:00160
|
part_of |
GO:0032991 protein-containing complex
|
PMID:17015622, PMID:3162913 |
PR:000000627
hTGFB1/var:R218H/Clv:1
Arg-218, CHEBI:29979
|
capable_of |
GO:0042803 protein homodimerization activity
|
PMID:11278244 |
capable_of |
GO:0005160 transforming growth factor beta receptor binding
|
PMID:11278244 |
capable_of |
GO:0008083 growth factor activity
increased relative to PR:000000616 TGFB1/iso:1/mature
|
PMID:12493741, PMID:12843182 |
located_in |
GO:0005615 extracellular space
|
PMID:11278244 |
participates_in |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:11278244 |
PR:000000619
hTGFB1/var:T81H/Clv:1
Tyr-81, CHEBI:29979
|
has_agent |
SO:0001558 polypeptide_localization_variant
|
PMID:12493741 |
PR:000000182
TGFB1
|
participates_in |
GO:0008283 cell population proliferation
|
PANTHER:PTHR11848:SF32 |
participates_in |
GO:0030154 cell differentiation
|
PANTHER:PTHR11848:SF32 |
Biological Process GO Term |
Protein Forms & Complexes |
Evidence |
GO:0030154 cell differentiation
|
PR:000000182
TGFB1
|
PANTHER:PTHR11848:SF32 |
GO:0043066 negative regulation of apoptotic process
|
PR:000000400
hTGFB1/var:R218C
Arg-218, CHEBI:29950
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000402
hTGFB1/var:H222D
His-222, CHEBI:29958
|
PMID:12493741 |
PR:000000403
hTGFB1/var:C225R
Cys-225, CHEBI:29952
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000623
hTGFB1/var:H222D/Clv:1
His-222, CHEBI:29958
|
PMID:12493741 |
PR:000025927
hTGFB1/iso:1/mature
|
PMID:9918798 |
PR:P01137-1
hTGFB1/iso:1
|
PMID:9918798 |
GO:0008283 cell population proliferation
|
PR:000000182
TGFB1
|
PANTHER:PTHR11848:SF32 |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PR:000000398
hTGFB1/var:L10P
Leu-10, CHEBI:50342
|
PMID:9783545 |
PR:000000399
hTGFB1/var:T81H
Tyr-81, CHEBI:29979
|
PMID:11062463 |
PR:000000400
hTGFB1/var:R218C
Arg-218, CHEBI:29950
|
PMID:12843182 |
PR:000000402
hTGFB1/var:H222D
His-222, CHEBI:29958
|
PMID:12493741 |
PR:000000403
hTGFB1/var:C225R
Cys-225, CHEBI:29952
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000621
hTGFB1/var:R218C/Clv:1
Arg-218, CHEBI:29950
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000623
hTGFB1/var:H222D/Clv:1
His-222, CHEBI:29958
|
PMID:12493741 |
PR:000000627
hTGFB1/var:R218H/Clv:1
Arg-218, CHEBI:29979
|
PMID:11278244 |
PR:000025927
hTGFB1/iso:1/mature
|
PMID:8471846 |
PR:000026335
hTGFB1/iso:1/inactive
Asn-82, MOD:00160
|
PMID:3162913 |
PR:P01137-1
hTGFB1/iso:1
|
PMID:1544940 |
Cellular Location GO Term |
Protein Forms & Complexes |
Evidence |
GO:0005796 Golgi lumen
|
PR:P01137-1
hTGFB1/iso:1
|
PMID:1544940 |
GO:0031012 extracellular matrix
|
PR:000025927
hTGFB1/iso:1/mature
|
PMID:8294500 |
PR:000026335
hTGFB1/iso:1/inactive
Asn-82, MOD:00160
|
PMID:17015622, PMID:8294500 |
GO:0005615 extracellular space
|
PR:000000403
hTGFB1/var:C225R
Cys-225, CHEBI:29952
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000620
hTGFB1/var:T81H/Clv:2
Tyr-81, CHEBI:29979
|
PMID:12493741 |
PR:000000621
hTGFB1/var:R218C/Clv:1
Arg-218, CHEBI:29950
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000623
hTGFB1/var:H222D/Clv:1
His-222, CHEBI:29958
|
PMID:12493741 |
PR:000000625
hTGFB1/var:C225R/Clv:1
Cys-225, CHEBI:29952
|
PMID:11062463, PMID:12493741, PMID:12843182 |
PR:000000627
hTGFB1/var:R218H/Clv:1
Arg-218, CHEBI:29979
|
PMID:11278244 |
|
top
|