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Protein Ontology Report - mNRG1

PR:Q6DR99 - http://purl.obolibrary.org/obo/PR_Q6DR99
This page represents a class of proteins encompassing all the protein products of the NRG1 gene in mouse .
Ontology Information
PRO ID PR:Q6DR99 Show OBO stanza / PAF
PRO name neuregulin-1 (mouse)
Synonyms
PRO-short-label: mNRG1
EXACT: protein Nrg1 (mouse)
Definition A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of mouse. [OMA:Q6DR99, PRO:DNx]
PRO Category organism-gene
Parent PR:000029649 pro-neuregulin-1, membrane-bound isoform
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 6
organism-modification 8
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044824
mNRG1/iso:IIIbeta1a/precursor
participates_in GO:0045773 positive regulation of axon extension MGI:4461331, PMID:20610754
PR:000044840
mNRG1/iso:IIIbeta[1a/1c/3]
located_in GO:0030424 axon MGI:4461331, PMID:20610754
located_in GO:0044297 cell body MGI:4461331, PMID:20610754
located_in GO:0030673 axolemma MGI:3796800, PMID:18458158
located_in GO:0030425 dendrite MGI:4461331, PMID:20610754
located_in GO:0030424 axon MGI:3042336, PMID:15044753
participates_in NOT GO:0048709 oligodendrocyte differentiation MGI:4420197, PMID:18080294
participates_in GO:0060999 positive regulation of dendritic spine development MGI:4461331, PMID:20610754
participates_in GO:0060999 positive regulation of dendritic spine development MGI:3803029, PMID:18596162
participates_in GO:2000010 positive regulation of protein localization to cell surface MGI:3796800, PMID:18458158
participates_in GO:0001964 startle response MGI:3803029, PMID:18596162
participates_in GO:0008366 axon ensheathment MGI:3590355, PMID:16129398
participates_in GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling MGI:3796800, PMID:18458158
participates_in GO:0031643 positive regulation of myelination MGI:4420197, PMID:18080294
participates_in GO:0031643 positive regulation of myelination MGI:3590355, PMID:16129398
PR:000044821
mNRG1/iso:Ibeta1a/mature
located_in GO:0005576 extracellular region MGI:3625788, PMID:11116142
participates_in GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI:3625788, PMID:11116142
PR:000044843
mNRG1/Clv:intracellular
capable_of GO:0005515 protein binding with PR:O54941 mSMARCE1 MGI:4438553, PMID:19781646
located_in GO:0005634 nucleus MGI:4461331, PMID:20610754
participates_in GO:0022008 neurogenesis MGI:4438553, PMID:19781646
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4461331, PMID:20610754
participates_in NOT GO:0045773 positive regulation of axon extension MGI:4461331, PMID:20610754
participates_in GO:0022008 neurogenesis MGI:4438553, PMID:19781646
PR:Q6DR99
mNRG1
participates_in GO:0031643 positive regulation of myelination MGI:3042336, PMID:15044753
PR:Q6DR98
mNRG1/iso:Ibeta1a
located_in GO:0009897 external side of plasma membrane MGI:3625788, PMID:11116142
participates_in NOT GO:0031643 positive regulation of myelination MGI:3042336, PMID:15044753
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0001964 startle response PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3803029, PMID:18596162
GO:0045944 positive regulation of transcription by RNA polymerase II PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754
NOT GO:0031643 positive regulation of myelination PR:Q6DR98 mNRG1/iso:Ibeta1a

MGI:3042336, PMID:15044753
GO:0008366 axon ensheathment PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3590355, PMID:16129398
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3796800, PMID:18458158
GO:0045773 positive regulation of axon extension PR:000044824 mNRG1/iso:IIIbeta1a/precursor

MGI:4461331, PMID:20610754
GO:0022008 neurogenesis PR:000044843 mNRG1/Clv:intracellular

MGI:4438553, PMID:19781646
PR:000044843 mNRG1/Clv:intracellular

MGI:4438553, PMID:19781646
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation PR:000044821 mNRG1/iso:Ibeta1a/mature

MGI:3625788, PMID:11116142
GO:0031643 positive regulation of myelination PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4420197, PMID:18080294
PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3590355, PMID:16129398
PR:Q6DR99 mNRG1

MGI:3042336, PMID:15044753
NOT GO:0045773 positive regulation of axon extension PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754
GO:2000010 positive regulation of protein localization to cell surface PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3796800, PMID:18458158
GO:0060999 positive regulation of dendritic spine development PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4461331, PMID:20610754
PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3803029, PMID:18596162
NOT GO:0048709 oligodendrocyte differentiation PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4420197, PMID:18080294
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0030425 dendrite PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4461331, PMID:20610754
GO:0030673 axolemma PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3796800, PMID:18458158
GO:0044297 cell body PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4461331, PMID:20610754
GO:0005576 extracellular region PR:000044821 mNRG1/iso:Ibeta1a/mature

MGI:3625788, PMID:11116142
GO:0005634 nucleus PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754
GO:0009897 external side of plasma membrane PR:Q6DR98 mNRG1/iso:Ibeta1a

MGI:3625788, PMID:11116142
GO:0030424 axon PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:4461331, PMID:20610754
PR:000044840 mNRG1/iso:IIIbeta[1a/1c/3]

MGI:3042336, PMID:15044753

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