[Term]
id: PR:Q3URY7
name: neuregulin-1 type III-beta1c (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3URY7." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q3URY7]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta1c" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q3URY7
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000029649
name: pro-neuregulin-1, membrane-bound isoform
def: "A protein that is a translation product of the human NRG1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GGF" RELATED Gene-based []
synonym: "HGL" RELATED Gene-based []
synonym: "NDF" RELATED Gene-based []
synonym: "HRGA" RELATED Gene-based []
synonym: "NRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "SMDF" RELATED Gene-based []
synonym: "pro-NRG1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000044824
name: neuregulin-1 type III-beta1a precursor (mouse)
def: "A neuregulin-1 type III-beta1a (mouse) that has not been proteolytically processed." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q6DR99]
comment: Category=organism-modification.
synonym: "mNRG1/iso:IIIbeta1a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type III-beta1a precursor (mouse)" RELATED []
synonym: "neuregulin type III-beta1a precursor (mouse)" RELATED []
is_a: PR:Q6DR99-1 ! neuregulin-1 type III-beta1a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044825
name: neuregulin-1 type III-beta1c precursor (mouse)
def: "A neuregulin-1 type III-beta1c (mouse) that has not been proteolytically processed." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q3URY7]
comment: Category=organism-modification.
synonym: "mNRG1/iso:IIIbeta1c/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type III-beta1a precursor (mouse)" RELATED []
synonym: "neuregulin type III-beta1c precursor (mouse)" RELATED []
is_a: PR:Q3URY7 ! neuregulin-1 type III-beta1c (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044823
name: neuregulin-1 type I-beta1a transmembrane precursor (mouse)
def: "A neuregulin-1 type I-beta1a (mouse) that has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta1a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta1a precursor (mouse)" RELATED []
synonym: "neuregulin beta1a precursor (mouse)" RELATED []
is_a: PR:Q6DR98 ! neuregulin-1 type I-beta1a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044837
name: neuregulin-1 type I-beta4a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein described as NRG type I-beta4 in PMID:11116142." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG-beta4 (mouse)" RELATED [PMID:11116142]
synonym: "mNRG1/iso:Ibeta4a" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-beta4a (mouse)" RELATED []
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044821
name: neuregulin-1 type I-beta1a mature form (mouse)
def: "A neuregulin-1 type I-beta1a (mouse) that has been proteolytically processed by the Meltrin beta/ADAM19 metalloprotease to produce a soluble form consisting of the ectodomain." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta1a/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta1a mature form (mouse)" RELATED []
synonym: "neuregulin beta1a mature form (mouse)" RELATED []
is_a: PR:Q6DR98 ! neuregulin-1 type I-beta1a (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044839
name: neuregulin-1 type I-beta4a mature form (mouse)
def: "A neuregulin-1 type I-beta4a (mouse) that has been proteolytically processed by the Meltrin beta/ADAM19 metalloprotease to produced a soluble form consisting of the ectodomain." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta4a/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta4a mature form (mouse)" RELATED []
synonym: "neuregulin beta4a mature form (mouse)" RELATED []
is_a: PR:000044837 ! neuregulin-1 type I-beta4a (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044838
name: neuregulin-1 type I-beta4a precursor (mouse)
def: "A neuregulin-1 type I-beta4a (mouse) that is a transmembrane protein which has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta4a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-beta4a precursor (mouse)" RELATED []
is_a: PR:000044837 ! neuregulin-1 type I-beta4a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DR99-1
name: neuregulin-1 type III-beta1a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DR99-1." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q6DR99]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta1a" EXACT PRO-short-label [PRO:DAN]
synonym: "neuregulin-1 type III beta1-a (mouse)" EXACT [PRO:DAN, UniProtKB:Q6DR99]
xref: UniProtKB:Q6DR99-1
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8BX76
name: neuregulin-1 type III-beta3 (mouse)
def: "A neuregulin-1 type III-beta3 that is encoded in the genome of mouse." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q8BX76]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta3" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q8BX76
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044822 ! neuregulin-1 type III-beta3

[Term]
id: PR:000044840
name: neuregulin-1 type III (mouse)
def: "A neuregulin-1 (mouse) that has an N-terminal cystein-rich domain (CRD)." [PMID:15044753, PRO:KRC]
comment: Category=union.
synonym: "mNRG1/iso:IIIbeta[1a/1c/3]" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
union_of: PR:Q3URY7 ! neuregulin-1 type III-beta1c (mouse)
union_of: PR:Q6DR99-1 ! neuregulin-1 type III-beta1a (mouse)
union_of: PR:Q8BX76 ! neuregulin-1 type III-beta3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044841
name: neuregulin-1 type I-alpha2a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein described as NRG type I-alpha2 in PMID:11116142." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG-alpha2 (mouse)" RELATED [PMID:11116142]
synonym: "mNRG1/iso:Ialpha2a" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-alpha2a (mouse)" RELATED []
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044842
name: neuregulin-1 type I-alpha2a precursor (mouse)
def: "A neuregulin-1 type I-alpha2a (mouse) that is a transmembrane protein which has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ialpha2a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-alpha2a precursor (mouse)" RELATED []
is_a: PR:000044841 ! neuregulin-1 type I-alpha2a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044843
name: neuregulin-1 intracellular domain (mouse)
def: "A neuregulin-1 (mouse) that corresponds to the intracellular domain after proteolytic cleavage. UniProtKB:Q6DR99, 326-700." [PMID:20610754, PMID:24083437, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000205, based on PMID:24083437).
synonym: "NRG1 ICD (mouse)" RELATED []
synonym: "mNRG1/Clv:intracellular" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q6DR99, 326-700" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DR99
name: neuregulin-1 (mouse)
def: "A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of mouse." [OMA:Q6DR99, PRO:DNx]
comment: Category=organism-gene.
synonym: "mNRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Nrg1 (mouse)" EXACT [UniProtKB:Q6DR99]
xref: UniProtKB:Q6DR99
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform
relationship: has_gene_template MGI:96083 ! Nrg1 (mouse)

[Term]
id: PR:Q6DR98
name: neuregulin-1 type I-beta1a (mouse)
def: "A neuregulin-1 type I-beta1a that is encoded in the genome of mouse." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG beta1 (mouse)" RELATED []
synonym: "mNRG1/iso:Ibeta1a" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q6DR98
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044820 ! neuregulin-1 type I-beta1a