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Protein Ontology Report - mNRG1/Clv:intracellular

PR:000044843 - http://purl.obolibrary.org/obo/PR_000044843
Ontology Information
PRO ID PR:000044843 Show OBO stanza / PAF
PRO name neuregulin-1 intracellular domain (mouse)
Synonyms
PRO-short-label: mNRG1/Clv:intracellular
PRO-proteoform-std: UniProtKB:Q6DR99, 326-700
RELATED: NRG1 ICD (mouse)
Definition A neuregulin-1 (mouse) that corresponds to the intracellular domain after proteolytic cleavage. UniProtKB:Q6DR99, 326-700. [PMID:20610754, PMID:24083437, PRO:KRC]
Comment Evidence=(ECO:0000205, based on PMID:24083437).
PRO Category organism-modification
Parent PR:Q6DR99 neuregulin-1 (mouse)
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044843
mNRG1/Clv:intracellular
capable_of GO:0005515 protein binding with PR:O54941 mSMARCE1 MGI:4438553, PMID:19781646
located_in GO:0005634 nucleus MGI:4461331, PMID:20610754
participates_in GO:0022008 neurogenesis MGI:4438553, PMID:19781646
participates_in NOT GO:0045773 positive regulation of axon extension MGI:4461331, PMID:20610754
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4461331, PMID:20610754
participates_in GO:0022008 neurogenesis MGI:4438553, PMID:19781646
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0022008 neurogenesis PR:000044843 mNRG1/Clv:intracellular

MGI:4438553, PMID:19781646
PR:000044843 mNRG1/Clv:intracellular

MGI:4438553, PMID:19781646
NOT GO:0045773 positive regulation of axon extension PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754
GO:0045944 positive regulation of transcription by RNA polymerase II PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000044843 mNRG1/Clv:intracellular

MGI:4461331, PMID:20610754

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