Protein Ontology Report - hIRAK4 PR:Q9NWZ3 - http://purl.obolibrary.org/obo/PR_Q9NWZ3

This page represents a class of proteins encompassing all the protein products of the IRAK4 gene in human .

Ontology Information
PRO ID	PR:Q9NWZ3 Show OBO stanza / PAF
PRO name	interleukin-1 receptor-associated kinase 4 (human)
Synonyms	PRO-short-label: hIRAK4 EXACT: IRAK-4 (human); renal carcinoma antigen NY-REN-64 (human) Gene-based: IRAK4
Definition	An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human. [PRO:CNA]
PRO Category	organism-gene
Parent	PR:000001780 interleukin-1 receptor-associated kinase 4
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 3
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100193, HGNC:17967, UniProtKB:Q9NWZ3

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hIRAK4 forms found in complexes
hIRAK4 Component Complexes PR:000001780 IRAK4 PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex PR:000027184 hIRAK4/UnMod PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) PR:000027191 hIRAK4/iso:1/Phos:1 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) PR:000027191 hIRAK4/iso:1/Phos:1 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 PR:000001780 IRAK4 has_part Pfam:PF00069 Protein kinase domain has_part Pfam:PF00531 Death domain PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 Biological Process GO Term Protein Forms & Complexes Evidence GO:0034142 toll-like receptor 4 signaling pathway PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) Reactome:REACT_6894 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) Reactome:REACT_6894 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) Reactome:REACT_6894

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