PRO ID |
PR:000001013
Show OBO stanza
|
PRO name |
integrin alpha-X |
Synonyms |
PRO-short-label: |
ITGAX |
EXACT: |
CD11 antigen-like family member C; CD11c; Leu M5; leukocyte adhesion glycoprotein p150,95 alpha chain; leukocyte adhesion receptor p150,95 |
Gene-based: |
CD11C |
|
Definition |
An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
[UniProtKB:P20702]
|
Comment |
Requested by=CL. |
PRO Category |
gene |
Parent |
PR:000001005 integrin alpha with A domain |
Terms by PRO Category |
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Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
2 |
sequence
|
0 |
organism-sequence
|
0 |
modification
|
1 |
organism-modification
|
1 |
union
|
0 |
|
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