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Protein Ontology Report - integrin alpha with A domain

PR:000001005 - http://purl.obolibrary.org/obo/PR_000001005
Ontology Information
PRO ID PR:000001005 Show OBO stanza / PAF
PRO name integrin alpha with A domain
Synonyms
EXACT: integrin alpha with I domain
Definition An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. [PIRSF:PIRSF002497]
PRO Category family
Parent PR:000025796 integrin alpha
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000001005
integrin alpha with A domain
has_part Pfam:PF08441 Integrin alpha PIRSF:PIRSF002497
has_part Pfam:PF00092 von Willebrand factor type A domain PIRSF:PIRSF002497
has_part Pfam:PF00357 Integrin alpha cytoplasmic region PIRSF:PIRSF002497
has_part Pfam:PF01839 FG-GAP repeat PIRSF:PIRSF002497

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