[Term]
id: PR:000001013
name: integrin alpha-X
def: "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis." [UniProtKB:P20702]
comment: Category=gene. Requested by=CL.
synonym: "CD11C" RELATED Gene-based []
synonym: "CD11c" EXACT []
synonym: "ITGAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Leu M5" EXACT []
synonym: "CD11 antigen-like family member C" EXACT []
synonym: "leukocyte adhesion receptor p150,95" EXACT []
synonym: "leukocyte adhesion glycoprotein p150,95 alpha chain" EXACT []
xref: IUPHARobj:2454
is_a: PR:000001005 ! integrin alpha with A domain