iPTMnet Report for Q9Z0F8 (Adam17)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Z0F8 / ADA17_MOUSE
Protein Name Disintegrin and metalloproteinase domain-containing protein 17 precursor
Gene Name Name: Adam17
Synonyms:Tace;
Organism Mus musculus (Mouse)

PRO ID PR:Q9Z0F8
DAG View
PRO Name disintegrin and metalloproteinase domain-containing protein 17 (mouse)
Definition An ADAM 17 endopeptidase that is encoded in the genome of mouse.
Short Label mADAM17
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Z0F8 (Adam17) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
Y702 Phosphorylation PhosphoSitePlus   RLIMS-P 23868980
K728 Ubiquitination PhosphoSitePlus
T735 Phosphorylation Q63844 (Mapk3) phospho.ELM   PhosphoSitePlus   UniProt 21183079, 15923650
T764 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 19144319, 30355783
S811 Phosphorylation PhosphoSitePlus
S822 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9Z0F8 (Adam17) Y702 P06804 (Tnf) unknown eFIP 23868980