iPTMnet Report for Q9Y6X5 (ENPP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6X5 / ENPP4_HUMAN
Protein Name Bis(5'-adenosyl)-triphosphatase ENPP4 precursor
Gene Name Name: ENPP4
Synonyms:KIAA0879,NPP4;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6X5
DAG View
PRO Name bis(5'-adenosyl)-triphosphatase ENPP4 (human)
Definition A bis(5'-adenosyl)-triphosphatase ENPP4 that is encoded in the genome of human.
Short Label hENPP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6X5 (ENPP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
T68 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
N128 N-Glycosylation GlyGen 24190977
N155 N-Glycosylation GlyGen   UniProt 24190977, 24338010
N166 N-Glycosylation GlyGen   UniProt 24338010
N202 N-Glycosylation GlyGen 24190977
N276 N-Glycosylation GlyGen 24190977
N286 N-Glycosylation GlyGen 24190977
N327 N-Glycosylation GlyGen 24190977
N386 N-Glycosylation GlyGen   UniProt 24338010
S414 Phosphorylation IEDB 35494241
S433 Phosphorylation HPRD 17081983
S439 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T70 K70 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
N202 H202 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N276 I276 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S414 L414 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]