iPTMnet Report for Q9Y6W5 (WASF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6W5 / WASF2_HUMAN
Protein Name Actin-binding protein WASF2
Gene Name Name: WASF2
Synonyms:WAVE2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6W5
DAG View
PRO Name actin-binding protein WASF2 (human)
Definition An actin-binding protein WASF2 that is encoded in the genome of human.
Short Label hWASF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6W5 (WASF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T17 Phosphorylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation RLIMS-P 28332566
T129 Phosphorylation PhosphoSitePlus
T137 Phosphorylation neXtProt 18701695
Y139 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 16899465, 15657136, 28332566
Y150 Phosphorylation A0A173G4P4 (Abl fusion) phospho.ELM 15657136
Y150 Phosphorylation P00519 (ABL1) neXtProt 15657136
Y155 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S296 Phosphorylation neXtProt   PhosphoSitePlus 21419341
S296 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 21419341
S298 Phosphorylation PhosphoSitePlus
S308 Phosphorylation neXtProt   PhosphoSitePlus 21419341
S308 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 21419341
S343 Phosphorylation PRO   PhosphoSitePlus 21419341
S343 Phosphorylation P27361 (MAPK3) PhosphoSitePlus 21419341
T346 Phosphorylation PRO   PhosphoSitePlus 21419341
T346 Phosphorylation P27361 (MAPK3) PhosphoSitePlus 21419341
S351 Phosphorylation PhosphoSitePlus 21419341
S351 Phosphorylation P27361 (MAPK3) PhosphoSitePlus 21419341
S429 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
T471 Phosphorylation IEDB   PhosphoSitePlus 31848261
S474 Phosphorylation PhosphoSitePlus   UniProt 23186163
S482 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19012317
S482 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19012317
S484 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19012317
S484 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19012317
S488 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19012317
S488 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19012317
S489 Phosphorylation PhosphoSitePlus   RLIMS-P 19012317
S489 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 19012317
S497 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19012317
S497 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19012317
Site PTM Type PTM Enzyme Score Source PMID
T80 Phosphorylation HPRD 20068231
S292 Phosphorylation HPRD 19651622
S308 Phosphorylation HPRD 19651622
S442 Phosphorylation HPRD 20068231
S482 Phosphorylation HPRD 17081983
S484 Phosphorylation HPRD 17081983
S488 Phosphorylation HPRD 17081983
S489 Phosphorylation HPRD 17081983


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049671 (hWASF2/Phos:1) pY150 PRO
PR:000049672 (hWASF2/Phos:2) pY150,pS343,pT346 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q14247 (CTTN) S418 Q9Y6W5 (WASF2) unknown eFIP 26490115


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y150 C150 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y155 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S351 L351 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S429 F429 Biomuta DOID:4159 / skin cancer [ cosmic ]
S429 C429 Biomuta DOID:10534 / stomach cancer [ cosmic ]