iPTMnet Report for Q9Y6W3 (CAPN7)
Protein Information
| UniProt AC / UniProt ID | Q9Y6W3 / CAN7_HUMAN |
| Protein Name | Calpain-7 |
| Gene Name | Name: CAPN7 Synonyms:PALBH; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y6W3 |
| PRO Name | calpain-7 (human) |
| Definition | A calpain-7 that is encoded in the genome of human. |
| Short Label | hCAPN7 |
| Category | organism-gene |
Q9Y6W3 (CAPN7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| Y42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T95 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| C120 | Methylation | score1 | IEDB | 31844290 | ||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K156 | Acetylation | score1 | PhosphoSitePlus | |||
| K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S162 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C242 | Methylation | score1 | IEDB | 31844290 | ||
| K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K320 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K344 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S414 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T416 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K477 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y489 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K495 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K556 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K596 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K617 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y619 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y620 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y627 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S635 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K641 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y659 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y667 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K695 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S697 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S700 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K712 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K723 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y42 | H42 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K130 | N130 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K331 | E331 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K356 | N356 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S412 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S414 | I414 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y489 | C489 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K617 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K723 | N723 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View