iPTMnet Report for Q9Y6V7 (DDX49)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6V7 / DDX49_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX49
Gene Name Name: DDX49
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6V7
DAG View
PRO Name probable ATP-dependent RNA helicase DDX49 (human)
Definition A probable ATP-dependent RNA helicase DDX49 that is encoded in the genome of human.
Short Label hDDX49
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6V7 (DDX49) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
C73 Methylation IEDB 31844290
T127 Phosphorylation PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
R310 Methylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
C395 Methylation IEDB 31844290
K414 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K444 Methylation PhosphoSitePlus
R467 Methylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S272 R272 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R310 W310 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K421 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S470 A470 Biomuta DOID:4159 / skin cancer [ cosmic ]