iPTMnet Report for Q9Y6V0 (PCLO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6V0 / PCLO_HUMAN
Protein Name Protein piccolo
Gene Name Name: PCLO
Synonyms:ACZ;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6V0
DAG View
PRO Name protein piccolo (human)
Definition A protein piccolo that is encoded in the genome of human.
Short Label hPCLO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6V0 (PCLO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
K370 Acetylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
T615 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S619 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S656 Phosphorylation PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
T667 O-Glycosylation GlyGen 28657654
T668 O-Glycosylation GlyGen 28657654
S670 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
K841 Ubiquitination PhosphoSitePlus
T860 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
T921 Phosphorylation PhosphoSitePlus
T922 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
T1293 Phosphorylation PhosphoSitePlus
K1318 Acetylation PhosphoSitePlus
K1328 Acetylation PhosphoSitePlus
K1345 Acetylation PhosphoSitePlus
S1351 Phosphorylation PhosphoSitePlus
S1407 Phosphorylation PhosphoSitePlus
S1522 Phosphorylation PhosphoSitePlus
K1528 Methylation PhosphoSitePlus
T1531 Phosphorylation PhosphoSitePlus
S1532 Phosphorylation PhosphoSitePlus
S1535 Phosphorylation PhosphoSitePlus
Y1541 Phosphorylation PhosphoSitePlus
S1546 Phosphorylation PhosphoSitePlus
S1549 Phosphorylation PhosphoSitePlus
S1587 Phosphorylation PhosphoSitePlus
S1628 Phosphorylation PhosphoSitePlus
T1675 Phosphorylation PhosphoSitePlus
Y1680 Phosphorylation PhosphoSitePlus
S1681 Phosphorylation PhosphoSitePlus
S1684 Phosphorylation PhosphoSitePlus
S1685 Phosphorylation PhosphoSitePlus
S1802 Phosphorylation PhosphoSitePlus
S1803 Phosphorylation PhosphoSitePlus
K1809 Acetylation PhosphoSitePlus
S1831 Phosphorylation PhosphoSitePlus
S1837 Phosphorylation PhosphoSitePlus
T1839 Phosphorylation PhosphoSitePlus
Y1955 Phosphorylation PhosphoSitePlus
T1964 Phosphorylation PhosphoSitePlus
Y2000 Phosphorylation PhosphoSitePlus
T2250 Phosphorylation PhosphoSitePlus
S2258 Phosphorylation PhosphoSitePlus
S2290 Phosphorylation PhosphoSitePlus
S2382 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S2384 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S2402 Phosphorylation PhosphoSitePlus
S2432 Phosphorylation PhosphoSitePlus
S2447 Phosphorylation PhosphoSitePlus
T2461 O-Glycosylation GlyGen 28657654
T2476 O-Glycosylation GlyGen 28657654
T2480 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
T2548 O-Glycosylation GlyGen 28657654
S2598 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S2608 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
T2682 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S2750 O-Glycosylation GlyGen 28657654
T2759 O-Glycosylation GlyGen 28657654
T2796 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S2829 O-Glycosylation GlyGen 28657654
T2911 O-Glycosylation GlyGen 28657654
T2911 Phosphorylation PhosphoSitePlus
S2918 Phosphorylation PhosphoSitePlus
T2921 Phosphorylation PhosphoSitePlus
T2961 O-Glycosylation GlyGen 28657654
S2995 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
T3031 O-Glycosylation GlyGen 28657654
T3032 O-Glycosylation GlyGen 28657654
S3039 O-Glycosylation GlyGen 28657654
S3040 O-Glycosylation GlyGen 28657654
S3054 O-Glycosylation GlyGen 28657654
S3054 Phosphorylation PhosphoSitePlus
T3105 O-Glycosylation GlyGen 28657654
T3331 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
K3438 Acetylation PhosphoSitePlus
S3471 Phosphorylation PhosphoSitePlus
T3474 Phosphorylation PhosphoSitePlus
S3615 Phosphorylation PhosphoSitePlus
S3619 Phosphorylation PhosphoSitePlus
S3625 Phosphorylation PhosphoSitePlus
S3628 Phosphorylation PhosphoSitePlus
S3631 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
S3631 Phosphorylation PhosphoSitePlus
S3678 Phosphorylation PhosphoSitePlus
S3686 Phosphorylation PhosphoSitePlus
T3700 O-Glycosylation GlyGen 28657654
S3835 Phosphorylation PhosphoSitePlus
T3845 O-Glycosylation GlyGen 30379171
S3907 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
T3967 O-Glycosylation GlyGen 28657654
T3975 O-Glycosylation GlyGen 28657654, 20563614
S3976 O-Glycosylation GlyGen 20563614
S3992 O-Glycosylation GlyGen 28657654
S4023 O-Glycosylation GlyGen 28411811, 30379171, 29351928, ...20563614, 29485866, 28657654
T4092 O-Glycosylation GlyGen 28657654
T4221 Phosphorylation PhosphoSitePlus
T4224 Phosphorylation PhosphoSitePlus
S4231 Phosphorylation PhosphoSitePlus
S4296 Phosphorylation PhosphoSitePlus
S4297 Phosphorylation PhosphoSitePlus
S4313 O-Glycosylation GlyGen 30379171
S4334 Phosphorylation PhosphoSitePlus
T4337 Phosphorylation PhosphoSitePlus
S4341 Phosphorylation PhosphoSitePlus
S4345 Phosphorylation PhosphoSitePlus
S4347 Phosphorylation PhosphoSitePlus
S4385 O-Glycosylation GlyGen 28657654
S4659 Phosphorylation PhosphoSitePlus
S4846 Phosphorylation PhosphoSitePlus
S4864 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S138 Phosphorylation HPRD 20068231
S2402 Phosphorylation HPRD 20058876
S2432 Phosphorylation HPRD 20058876
S4864 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S138 Phosphorylation HPRD 20068231
S2402 Phosphorylation HPRD 20058876
S2432 Phosphorylation HPRD 20058876
S4864 Phosphorylation HPRD 20068231
T4902 Phosphorylation PhosphoSitePlus
S4931 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S138 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S167 F167 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T189 N189 Biomuta DOID:1324 / lung cancer [ cosmic ]
T189 I189 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T283 A283 Biomuta DOID:3571 / liver cancer [ cosmic ]
S429 F429 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S683 F683 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S769 L769 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S895 F895 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T922 P922 Biomuta [ cosmic ] DOID:4362 / cervical cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
K1318 R1318 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1351 F1351 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1522 L1522 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1531 P1531 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1535 P1535 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1546 N1546 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1549 L1549 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1587 R1587 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1587 C1587 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1675 S1675 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1684 L1684 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1802 T1802 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1802 G1802 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1803 Y1803 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1831 T1831 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1831 F1831 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1955 F1955 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1964 A1964 Biomuta DOID:363 / uterine cancer [ icgc ]
T1964 M1964 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T1964 R1964 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2258 I2258 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S2384 P2384 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2384 F2384 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2402 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2432 L2432 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2432 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2608 L2608 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2829 * Biomuta DOID:3953 / adrenal gland cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S2918 R2918 Biomuta DOID:263 / kidney cancer [ cosmic ]
T2921 I2921 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S2995 Y2995 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T3031 N3031 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T3032 K3032 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S3054 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S3471 N3471 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S3615 F3615 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S3619 F3619 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ]
S3631 L3631 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S3678 Y3678 Biomuta DOID:363 / uterine cancer [ icgc ]
S4023 N4023 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T4092 P4092 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T4092 I4092 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
T4224 N4224 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S4231 F4231 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S4296 F4296 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4313 Y4313 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S4313 F4313 Biomuta DOID:4159 / skin cancer [ cosmic ]
T4337 I4337 Biomuta DOID:4159 / skin cancer [ cosmic ]
T4337 P4337 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S4659 F4659 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4864 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]