iPTMnet Report for Q9Y6T7 (DGKB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6T7 / DGKB_HUMAN
Protein Name Diacylglycerol kinase beta
Gene Name Name: DGKB
Synonyms:DAGK2,KIAA0718;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6T7
DAG View
PRO Name diacylglycerol kinase beta (human)
Definition A diacylglycerol kinase beta that is encoded in the genome of human.
Short Label hDGKB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6T7 (DGKB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K113 Ubiquitination PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
K408 Methylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
Y461 Phosphorylation PhosphoSitePlus
Y586 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 T113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S403 F403 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S403 Y403 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K408 T408 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y586 F586 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S588 F588 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]