iPTMnet Report for Q9Y6M4 (CSNK1G3)
Protein Information
| UniProt AC / UniProt ID | Q9Y6M4 / KC1G3_HUMAN |
| Protein Name | Casein kinase I isoform gamma-3 |
| Gene Name | Name: CSNK1G3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y6M4 |
| PRO Name | casein kinase I isoform gamma-3 (human) |
| Definition | A casein kinase I isoform gamma-3 that is encoded in the genome of human. |
| Short Label | hCSNK1G3 |
| Category | organism-gene |
Q9Y6M4 (CSNK1G3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T29 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S31 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K48 | Acetylation | score1 | PhosphoSitePlus | |||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y64 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K91 | Methylation | score1 | PhosphoSitePlus | |||
| Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y203 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| A254 | Phosphorylation | score1 | UniProt | 20068231 | ||
| T256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K263 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R291 | Phosphorylation | score1 | UniProt | 20068231 | ||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S344 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| H366 | Phosphorylation | score1 | UniProt | 20068231 | ||
| R367 | Phosphorylation | score1 | UniProt | 20068231 | ||
| S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S397 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S398 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S413 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
| T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K436 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T29 | Phosphorylation | score0 | HPRD | 18691976, 18669648 | ||
| S31 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S32 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S34 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T256 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S344 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S413 | Phosphorylation | score0 | HPRD | 18691976 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T29 | Phosphorylation | score0 | HPRD | 18691976, 18669648 | ||
| S31 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S32 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S34 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T256 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S344 | Phosphorylation | score0 | HPRD | 18691976 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T29 | Phosphorylation | score2 | HPRD phospho.ELM | 18691976, 18669648 | ||
| S31 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
| S32 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S34 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
| Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T256 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S344 | Phosphorylation | score0 | HPRD | 18691976 | ||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976, 18669648, 20068231 | ||
| S366 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976, 18669648, 20068231 | ||
| T367 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976, 17081983, 20068231, ... | ||
| T373 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S11 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K61 | E61 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y64 | F64 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K253 | N253 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| A254 | T254 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K263 | N263 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K263 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K263 | E263 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R367 | M367 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S392 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K436 | N436 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View