iPTMnet Report for Q9Y6L6 (SLCO1B1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6L6 / SO1B1_HUMAN
Protein Name Solute carrier organic anion transporter family member 1B1
Gene Name Name: SLCO1B1
Synonyms:LST1,OATP1B1,OATP2,OATPC,SLC21A6;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6L6
DAG View
PRO Name solute carrier organic anion transporter family member 1B1 (human)
Definition A solute carrier organic anion transporter family member 1B1 that is encoded in the genome of human.
Short Label hSLCO1B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6L6 (SLCO1B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N134 N-Glycosylation GlyGen   UniProt 23285087
S293 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 24275569
S295 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 24275569
T301 Phosphorylation HPRD   PhosphoSitePlus 20166139
T312 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
N503 N-Glycosylation GlyGen   UniProt 23285087
N516 N-Glycosylation GlyGen   UniProt 23285087
Y625 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
Y640 Phosphorylation PhosphoSitePlus
Y645 Phosphorylation PhosphoSitePlus
S659 Phosphorylation HPRD   PhosphoSitePlus 20166139
S663 Phosphorylation HPRD   PhosphoSitePlus 20166139
S672 Phosphorylation PhosphoSitePlus   UniProt 24275569
S682 Phosphorylation PhosphoSitePlus   UniProt 24275569
S687 Phosphorylation PhosphoSitePlus
T689 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T301 K301 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T323 A323 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S328 F328 Biomuta DOID:4159 / skin cancer [ cosmic ]
S420 P420 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
S420 F420 Biomuta DOID:5041 / esophageal cancer [ cosmic ]