iPTMnet Report for Q9Y6I4 (USP3)
Protein Information
UniProt AC / UniProt ID | Q9Y6I4 / UBP3_HUMAN |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 3 |
Gene Name | Name: USP3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y6I4 |
PRO Name | ubiquitin carboxyl-terminal hydrolase 3 (human) |
Definition | A ubiquitin carboxyl-terminal hydrolase 3 that is encoded in the genome of human. |
Short Label | hUSP3 |
Category | organism-gene |
Q9Y6I4 (USP3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
T93 | Phosphorylation | score1 | PhosphoSitePlus | |||
K107 | Sumoylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
K333 | Ubiquitination | score1 | PhosphoSitePlus | |||
K354 | Methylation | score1 | PhosphoSitePlus | |||
K354 | Ubiquitination | score1 | PhosphoSitePlus | |||
S363 | Phosphorylation | score1 | PhosphoSitePlus | |||
T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S37 | N37 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K59 | Q59 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
S124 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K132 | T132 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T141 | A141 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S210 | G210 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K354 | N354 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S363 | L363 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |