iPTMnet Report for Q9Y6F6 (IRAG1)
Protein Information
UniProt AC / UniProt ID | Q9Y6F6 / IRAG1_HUMAN |
Protein Name | Inositol 1,4,5-triphosphate receptor associated 1 |
Gene Name | Name: IRAG1 Synonyms:IRAG,JAW1L,MRVI1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y6F6 |
PRO Name | inositol 1,4,5-triphosphate receptor associated 1 (human) |
Definition | An inositol 1,4,5-triphosphate receptor associated 1 that is encoded in the genome of human. |
Short Label | hIRAG1 |
Category | organism-gene |
Q9Y6F6 (IRAG1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S312 | Phosphorylation | score1 | PhosphoSitePlus | |||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
S386 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 16990611, 24275569 | ||
S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
K400 | Ubiquitination | score1 | PhosphoSitePlus | |||
K417 | Acetylation | score1 | PhosphoSitePlus | |||
K421 | Acetylation | score1 | PhosphoSitePlus | |||
K424 | Acetylation | score1 | PhosphoSitePlus | |||
S481 | Phosphorylation | score1 | PhosphoSitePlus | |||
S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
S657 | Phosphorylation | score2 | neXtProt | 16990611 | ||
S657 | Phosphorylation | Q13976 (PRKG1) | score2 | neXtProt | 16990611 | |
S676 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 16990611 | ||
S689 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 16990611, 11309393 | ||
S726 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000026855 (hIRAG1/iso:1/Phos:1) | pS657,pS670 | PRO | 16990611 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S189 | R189 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S199 | I199 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S312 | N312 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S386 | F386 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S657 | * | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |