Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6A9 / SPCS1_HUMAN
Protein Name Signal peptidase complex subunit 1
Gene Name Name: SPCS1
Synonyms:SPC12;ORFNames:HSPC033;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6A9
DAG View
PRO Name signal peptidase complex subunit 1 (human)
Definition A signal peptidase complex subunit 1 that is encoded in the genome of human.
Short Label hSPCS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6A9 (SPCS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K94 Acetylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 * Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]