Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6A5 / TACC3_HUMAN
Protein Name Transforming acidic coiled-coil-containing protein 3
Gene Name Name: TACC3
Synonyms:ERIC1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6A5
DAG View
PRO Name transforming acidic coiled-coil-containing protein 3 (human)
Definition A transforming acidic coiled-coil-containing protein 3 that is encoded in the genome of human.
Short Label hTACC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6A5 (TACC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S25 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18220336, ...18669648, 20068231
T30 O-Glycosylation GlyGen 31373491
T30 Phosphorylation PhosphoSitePlus
R32 Methylation PhosphoSitePlus
S34 Phosphorylation RLIMS-P 26134678
S39 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K51 Methylation PhosphoSitePlus
K54 Methylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
T59 Phosphorylation HPRD   PhosphoSitePlus 20068231, 17924679
T66 Phosphorylation PhosphoSitePlus
S71 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18212344, 19664995, ...18669648, 20068231
S73 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S175 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19690332, 20068231
S177 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163, ...20068231
S187 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
C206 S-Nitrosylation dbSNO 26338901
T216 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
T249 Phosphorylation HPRD   PhosphoSitePlus 19664995
S250 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19664995, ...20068231
T315 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20058876, 20068231
S317 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...20058876, 19664995, 18669648, 19415658, 20068231
S361 Phosphorylation IEDB 27920218
S402 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
Y403 Phosphorylation PhosphoSitePlus
K423 Acetylation PhosphoSitePlus
S424 O-Glycosylation GlyGen 23301498, 34019948, 31373491
C426 S-Nitrosylation dbSNO 26338901
S427 O-Glycosylation GlyGen 31373491
S434 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 16964243, ...15302935, 19664994, 19664995, 18669648, 19415658
T437 Phosphorylation PhosphoSitePlus
C459 Methylation IEDB 31844290
T481 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T496 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
Y540 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
S552 Phosphorylation HPRD   RLIMS-P 26134678, 20068231
S558 Phosphorylation O14965 (AURKA) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 25596274, 26134678, 23186163, ...18212344, 23861900, 23918938, 17545617, 18669648, 20566684, 29510984, 31823729
Y560 Phosphorylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
T590 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
Y739 Phosphorylation HPRD   PhosphoSitePlus 20068231
K748 Ubiquitination PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9Y6A5 (TACC3) S558 Q00610 (CLTC) unknown eFIP 23861900